O:9:"MagpieRSS":24:{s:6:"parser";i:0;s:12:"current_item";a:0:{}s:5:"items";a:10:{i:0;a:11:{s:5:"title";s:101:"AMADEUS on the Sanremo 2022 Festival. From Tommaso Paradiso co-host to the quarrels behind the scenes";s:4:"link";s:138:"https://celebritynews.fuzzyskunk.com/amadeus-on-the-sanremo-2022-festival-from-tommaso-paradiso-co-host-to-the-quarrels-behind-the-scenes/";s:2:"dc";a:1:{s:7:"creator";s:10:"Tom Pauler";}s:7:"pubdate";s:31:"Sat, 18 Dec 2021 03:37:54 +0000";s:8:"category";s:62:"MusicAmadeuscohostFestivalParadisoquarrelsSanremoscenesTommaso";s:4:"guid";s:45:"https://celebritynews.fuzzyskunk.com/?p=19453";s:11:"description";s:768:"After having revealed what was said by Amadeus on the individual singers of the cast of Sanremo 2022 to the microphones of Password, well-known program of Rtl 102.5, let&#8217;s find out the statements of the artistic director on. To the question &#8220;How do you prepare for the Sanremo Festival?&#8220;The presenter replied: Among young people, an ... <a title="AMADEUS on the Sanremo 2022 Festival. From Tommaso Paradiso co-host to the quarrels behind the scenes" class="read-more" href="https://celebritynews.fuzzyskunk.com/amadeus-on-the-sanremo-2022-festival-from-tommaso-paradiso-co-host-to-the-quarrels-behind-the-scenes/" aria-label="More on AMADEUS on the Sanremo 2022 Festival. From Tommaso Paradiso co-host to the quarrels behind the scenes">Read more</a>";s:7:"content";a:1:{s:7:"encoded";s:6667:"<div>
<p>After having revealed what was said by <strong>Amadeus</strong> on the individual singers of the cast of <span class="blue"><strong>Sanremo 2022</strong></span>  to the microphones of <strong><span class="blue">Password</span></strong>, well-known program of <strong>Rtl 102.5</strong>, let&#8217;s find out the statements of the artistic director on.</p>
<p>To the question &#8220;<em>How do you prepare for the Sanremo Festival?</em>&#8220;The presenter replied:</p>
<blockquote>
<p>Among young people, an average of 800 songs plus those of <span class="blue"><strong>Area Sanremo</strong></span>  then about 50 (here there must be a typo in the press release. The pieces presented a <span class="blue"><strong>Sanremo young</strong></span>  there were over 700 of those ad <span class="blue"><strong>Area Sanremo</strong></span>  over 400 of which 21 submitted to the judgment of <strong>Amadeus</strong> Ed.).</p>
<p>I listen to the songs several times, watch the videos and read the bio.</p>
</blockquote>
<p>On the big names, on the other hand, there is an obviously different methodology, he explains &#8230;</p>
<blockquote>
<p><em>Of the Bigs this year there were about 330 applications, of these I took 22. I listen to the songs at any time because I have to assimilate them a lot, no one has to listen to them, it&#8217;s a decision I make alone.  It is the most important and also the most difficult thing of the Festival in my opinion.  I want not to make a mistake in the composition of the singers in the competition, for me Sanremo starts from there.</em></p>
<p>I listen to songs everywhere: at home and in the car which is essential for me.  I work in Rome, I live in Milan and I often drive back and forth by car.  The moment I listen to a song while driving, I realize if I want to turn up the volume or if I get distracted: if I listen to a song and think about something else and the song is over, then it means that maybe it hasn&#8217;t captured me.  I take responsibility on my own for the songs I bring to Sanremo.</p>
<p>I have an author friend, <strong>Maximum</strong> <strong>Martelli</strong>, with whom I sometimes share thoughts, but he always tells me that I change my mind.  I often change my mind: I make a list, I show it to him, after four days the list is different.  He tells me I have to think for myself.  When my definitive list arrives, half of Sanremo is done for me.  How long does it take to get the list?  About a month and a half.</p>
<p>I talked to all the participants, they don&#8217;t have the thought of the ranking.  Everyone comes to bring their own music and to make it known to the public in the most important event we have.</p>
</blockquote>
<h2>Amadeus Sanremo 2022 SPOILERS AND CURIOSITIES</h2>
<p>Here are some of the more interesting questions asked by the hosts of <span class="blue"><strong>Password</strong></span>  or <strong>Nicoletta Deponti</strong>, <strong>Cecilia Songini</strong> e <strong>Niccolò Giustini</strong>:</p>
<p><strong>Tommaso Paradiso</strong> as a co-host?</p>
<blockquote>
<p>I like it when there are rumors.  I think I was already on stage before even starting with at least thirty ladies of the show and not only, also many friends.  It is right that this happens: Sanremo belongs to everyone and everyone must say what they think.  I neither confirm nor deny.</p>
</blockquote>
<p>Have you tried on your clothes yet?</p>
<blockquote>
<p>I chose the fabrics.  I let my wife choose the clothes, because I am also a bit color blind, in fact I always wear black and blue.  I have to see the strong colors: the strong yellow I see, the pastel colors mess with me a bit.  I will wear two dresses in the evening.</p>
</blockquote>
<p>Besides <strong>Bugo</strong> e <strong>Morgan</strong>, did a fight happen that we didn&#8217;t hear about?</p>
<blockquote>
<p>No, I must say that in Sanremo if you discuss you have to do it on stage.  I get mad if they do it behind the scenes.  Last year there was a great climate.  When the Festival is around I say it, I don&#8217;t even go to the bathroom.  If any technical problem occurs, what would I do?  I can never move.</p>
<p>When the discussion happened between <strong>Bugo</strong> e <strong>Morgan</strong> I was back there, I realized that the text was not that but I thought he had forgotten the words.  When <strong>Bugo</strong> went away I understood, <strong>Fiorello</strong> at that moment he was sleeping in the wings, we were almost at the end of the evening.  He woke up suddenly, didn&#8217;t know what had happened and chose to go on stage to improvise.</p>
</blockquote>
<p>There are absolute prohibitions to the <strong><span class="blue">Sanremo Festival</span></strong>?</p>
<blockquote>
<p>I consider that singers are artists and artists should not be limited.  I never censor any song, nor do I censor how I present a song.  I think they are all very intelligent, they know what to do: if there is something that goes in a direction of provocation it is clearly a moment of spectacle, there is no vulgarity or something out of place.  This is Sanremo too, today.</p>
<p>Sanremo must reflect what is the characteristic and personality of the singers in the competition.</p>
</blockquote>
<p>This year&#8217;s opinion poll jury &#8230;</p>
<blockquote>
<p>It will be a broader opinion poll, there will be a thousand.  There are more ways to vote, radios will also be present and they will vote too.  Why can&#8217;t the radio vote?  It is not possible that in a place where songs are made that will then go on the radio, there are no radios.  The radio must have the right to have its say within the Festival.</p>
<p>There will be the public at home, fundamental, remember that last year the televoting gave the victory to <strong>Moonlight</strong> and this is important.  There is no way to win Sanremo.  THE <strong>Moonlight</strong>?  They are a group that was already on the springboard, I have no credit for their success, I just chose their song.  They are now highly sought after.</p>
</blockquote>
</div>
<p>We  would love to  say thanks to the  writer of this  write-up for this  amazing content<br />
<br />
<a href="https://www.allmusicitalia.it/news/sanremo-2022-rtl-102-5-amadeus.html" target="_blank" rel="noopener">AMADEUS on the Sanremo 2022 Festival. From Tommaso Paradiso co-host to the quarrels behind the scenes<br />
</a></p>
<p><center><iframe loading="lazy" src="http://www.marketbase.interactivision.ro/feed2js/magpie_debug.php?url=https://celebritynews.fuzzyskunk.com/feed" height="25" width="250" title=""></iframe></center></p>
";}s:7:"summary";s:768:"After having revealed what was said by Amadeus on the individual singers of the cast of Sanremo 2022 to the microphones of Password, well-known program of Rtl 102.5, let&#8217;s find out the statements of the artistic director on. To the question &#8220;How do you prepare for the Sanremo Festival?&#8220;The presenter replied: Among young people, an ... <a title="AMADEUS on the Sanremo 2022 Festival. From Tommaso Paradiso co-host to the quarrels behind the scenes" class="read-more" href="https://celebritynews.fuzzyskunk.com/amadeus-on-the-sanremo-2022-festival-from-tommaso-paradiso-co-host-to-the-quarrels-behind-the-scenes/" aria-label="More on AMADEUS on the Sanremo 2022 Festival. From Tommaso Paradiso co-host to the quarrels behind the scenes">Read more</a>";s:12:"atom_content";s:6667:"<div>
<p>After having revealed what was said by <strong>Amadeus</strong> on the individual singers of the cast of <span class="blue"><strong>Sanremo 2022</strong></span>  to the microphones of <strong><span class="blue">Password</span></strong>, well-known program of <strong>Rtl 102.5</strong>, let&#8217;s find out the statements of the artistic director on.</p>
<p>To the question &#8220;<em>How do you prepare for the Sanremo Festival?</em>&#8220;The presenter replied:</p>
<blockquote>
<p>Among young people, an average of 800 songs plus those of <span class="blue"><strong>Area Sanremo</strong></span>  then about 50 (here there must be a typo in the press release. The pieces presented a <span class="blue"><strong>Sanremo young</strong></span>  there were over 700 of those ad <span class="blue"><strong>Area Sanremo</strong></span>  over 400 of which 21 submitted to the judgment of <strong>Amadeus</strong> Ed.).</p>
<p>I listen to the songs several times, watch the videos and read the bio.</p>
</blockquote>
<p>On the big names, on the other hand, there is an obviously different methodology, he explains &#8230;</p>
<blockquote>
<p><em>Of the Bigs this year there were about 330 applications, of these I took 22. I listen to the songs at any time because I have to assimilate them a lot, no one has to listen to them, it&#8217;s a decision I make alone.  It is the most important and also the most difficult thing of the Festival in my opinion.  I want not to make a mistake in the composition of the singers in the competition, for me Sanremo starts from there.</em></p>
<p>I listen to songs everywhere: at home and in the car which is essential for me.  I work in Rome, I live in Milan and I often drive back and forth by car.  The moment I listen to a song while driving, I realize if I want to turn up the volume or if I get distracted: if I listen to a song and think about something else and the song is over, then it means that maybe it hasn&#8217;t captured me.  I take responsibility on my own for the songs I bring to Sanremo.</p>
<p>I have an author friend, <strong>Maximum</strong> <strong>Martelli</strong>, with whom I sometimes share thoughts, but he always tells me that I change my mind.  I often change my mind: I make a list, I show it to him, after four days the list is different.  He tells me I have to think for myself.  When my definitive list arrives, half of Sanremo is done for me.  How long does it take to get the list?  About a month and a half.</p>
<p>I talked to all the participants, they don&#8217;t have the thought of the ranking.  Everyone comes to bring their own music and to make it known to the public in the most important event we have.</p>
</blockquote>
<h2>Amadeus Sanremo 2022 SPOILERS AND CURIOSITIES</h2>
<p>Here are some of the more interesting questions asked by the hosts of <span class="blue"><strong>Password</strong></span>  or <strong>Nicoletta Deponti</strong>, <strong>Cecilia Songini</strong> e <strong>Niccolò Giustini</strong>:</p>
<p><strong>Tommaso Paradiso</strong> as a co-host?</p>
<blockquote>
<p>I like it when there are rumors.  I think I was already on stage before even starting with at least thirty ladies of the show and not only, also many friends.  It is right that this happens: Sanremo belongs to everyone and everyone must say what they think.  I neither confirm nor deny.</p>
</blockquote>
<p>Have you tried on your clothes yet?</p>
<blockquote>
<p>I chose the fabrics.  I let my wife choose the clothes, because I am also a bit color blind, in fact I always wear black and blue.  I have to see the strong colors: the strong yellow I see, the pastel colors mess with me a bit.  I will wear two dresses in the evening.</p>
</blockquote>
<p>Besides <strong>Bugo</strong> e <strong>Morgan</strong>, did a fight happen that we didn&#8217;t hear about?</p>
<blockquote>
<p>No, I must say that in Sanremo if you discuss you have to do it on stage.  I get mad if they do it behind the scenes.  Last year there was a great climate.  When the Festival is around I say it, I don&#8217;t even go to the bathroom.  If any technical problem occurs, what would I do?  I can never move.</p>
<p>When the discussion happened between <strong>Bugo</strong> e <strong>Morgan</strong> I was back there, I realized that the text was not that but I thought he had forgotten the words.  When <strong>Bugo</strong> went away I understood, <strong>Fiorello</strong> at that moment he was sleeping in the wings, we were almost at the end of the evening.  He woke up suddenly, didn&#8217;t know what had happened and chose to go on stage to improvise.</p>
</blockquote>
<p>There are absolute prohibitions to the <strong><span class="blue">Sanremo Festival</span></strong>?</p>
<blockquote>
<p>I consider that singers are artists and artists should not be limited.  I never censor any song, nor do I censor how I present a song.  I think they are all very intelligent, they know what to do: if there is something that goes in a direction of provocation it is clearly a moment of spectacle, there is no vulgarity or something out of place.  This is Sanremo too, today.</p>
<p>Sanremo must reflect what is the characteristic and personality of the singers in the competition.</p>
</blockquote>
<p>This year&#8217;s opinion poll jury &#8230;</p>
<blockquote>
<p>It will be a broader opinion poll, there will be a thousand.  There are more ways to vote, radios will also be present and they will vote too.  Why can&#8217;t the radio vote?  It is not possible that in a place where songs are made that will then go on the radio, there are no radios.  The radio must have the right to have its say within the Festival.</p>
<p>There will be the public at home, fundamental, remember that last year the televoting gave the victory to <strong>Moonlight</strong> and this is important.  There is no way to win Sanremo.  THE <strong>Moonlight</strong>?  They are a group that was already on the springboard, I have no credit for their success, I just chose their song.  They are now highly sought after.</p>
</blockquote>
</div>
<p>We  would love to  say thanks to the  writer of this  write-up for this  amazing content<br />
<br />
<a href="https://www.allmusicitalia.it/news/sanremo-2022-rtl-102-5-amadeus.html" target="_blank" rel="noopener">AMADEUS on the Sanremo 2022 Festival. From Tommaso Paradiso co-host to the quarrels behind the scenes<br />
</a></p>
<p><center><iframe loading="lazy" src="http://www.marketbase.interactivision.ro/feed2js/magpie_debug.php?url=https://celebritynews.fuzzyskunk.com/feed" height="25" width="250" title=""></iframe></center></p>
";s:14:"date_timestamp";i:1639798674;}i:1;a:11:{s:5:"title";s:39:"BARBARA KRUGER OR THE POWER OF THE WORD";s:4:"link";s:77:"https://celebritynews.fuzzyskunk.com/barbara-kruger-or-the-power-of-the-word/";s:2:"dc";a:1:{s:7:"creator";s:11:"Harold Kent";}s:7:"pubdate";s:31:"Sat, 18 Dec 2021 03:07:45 +0000";s:8:"category";s:40:"Influential PeopleBarbaraKrugerpowerword";s:4:"guid";s:45:"https://celebritynews.fuzzyskunk.com/?p=19447";s:11:"description";s:546:"The American artist Barbara Kruger is a conceptual artist, who lives and works between Los Angeles and New York, right now she is working on one of the most important exhibitions on her career, which will be hosted in 2020 by the Art Institute of Chicago. Barbara Kruger&#8217;s work is one of the most recognized ... <a title="BARBARA KRUGER OR THE POWER OF THE WORD" class="read-more" href="https://celebritynews.fuzzyskunk.com/barbara-kruger-or-the-power-of-the-word/" aria-label="More on BARBARA KRUGER OR THE POWER OF THE WORD">Read more</a>";s:7:"content";a:1:{s:7:"encoded";s:5137:"<div id="">
<p style="text-align: justify;">The American artist <strong>Barbara Kruger</strong> is a conceptual artist, who lives and works between Los Angeles and New York, right now she is working on one of the most important exhibitions on her career, which will be hosted in 2020 by the Art Institute of Chicago. <strong>Barbara Kruger&#8217;s work is one of the most recognized in contemporary art since the 70s, with her work she resorts to the power of the word, always questioning the established patterns and powers.</strong> His works are based on provocative phrases or comments that criticize the consumer society and indiscriminate abuses of power.</p>
<p style="text-align: justify;">Kruger&#8217;s work is impossible to understand without accepting the relationship he establishes between art and advertising, thus appropriating images from advertising media, cinema or television. <strong>In his work he proposes questions that today in the XXI century, we still have not been able to respond by addressing issues such as stereotyping, politics, the question of power, sexuality or representation.</strong> Following her training at Syracuse University (New York), she continued her career as a graphic designer, becoming chief designer at Mademoiselle magazine in New York.  In the 1960s and 1970s, she also explored her interest in poetry, inspired by Patty Smith and involved, in some way, with the feminist movement of the time.<strong> It was precisely at the end of the 70s, when Barbara Kruger began to establish a very clear line in her work. <br /></strong></p>
<p style="text-align: center;">
<p style="text-align: center;"><span style="font-size: 8pt;"> © Barbara Kruger</span></p>
<p style="text-align: justify;"><strong>  Through appropriate images, many of them in black and white, he introduces red, black or white text, which immediately provoke the viewer to react to an intelligent and direct approach that questions him about feminism, classism, consumerism, individual autonomy and desire. .  In his works we can find slogans such as: &#8220;Your body is a battleground&#8221; or &#8220;I shop therefore I am&#8221; (I buy, therefore I exist).  For Barbara Kruger, the woman is nothing other than a victim of a patriarchal system that objectifies her.  This is evident in his work made in 1989, entitled Untitled (Your Body is a Battleground), in which he uses a large image with the face of a model that he divides into sections.  In the image you can read the phrase &#8220;Your body is a battlefield&#8221;, thus questioning that objectification to which women are subjected and vindicating the reproductive rights of women.</strong></p>
</p>
<p style="text-align: center;"><strong><img src="http://www.madridartprocess.com/images/BARBARA-KRUGER-12.jpg" alt="BARBARA KRUGER 12" title="BARBARA KRUGER OR THE POWER OF THE WORD 2"></strong></p>
<p style="text-align: center;"><span style="font-size: 8pt;">© Barbara Kruger</span></p>
<p style="text-align: justify;">Barbara Kruger&#8217;s work is testament to the deconstructivist concerns that ran much of the feminist art of the 1980s and 1990s.  Influenced by writers such as Foucault, Baudrillard, Kristeva, Lacan and Derrida, she seeks to manipulate and recontextualize images, to question the way in which power represents female identity.  In 1975 her artistic work began to be different, acquiring a certain value of abstraction, a period of experimentation began, which led her to rethink her creative process and what it meant to ?call herself an artist?.  At the same time, his works were influenced by the work of artists such as Carol Squiers, Lynne Tillman, Rainer, Akerman or Mary Kelly.<strong> Already in the 80s, Kruger&#8217;s work became more popular after participating in Documenta VII, his work began to enter the commercial sphere of art.  This made the artist received criticism because she criticized the consumer society.  She has always defended saying that being part of the market meant being part of the gear, therefore more turned out to be a ploy to spread their message.  Within this context and exploring the relationship between space and violence, his work also appeared in museums and galleries around the world, where he proclaims his speech, has been on Billboards, posters, public parks, railway stations and other public places.</strong></p>
<p style="text-align: left;"><span style="color: #808080; font-size: 8pt;"><span style="color: #000000; font-family: arial black,sans-serif;"><strong>Eduardo Álvarez |  September 12, 2018</strong></span></span></p>
</p></div>
<p>We would like to  say thanks to the author of this  short article for this  remarkable  web content<br />
<br />
<a href="http://www.madridartprocess.com/tendencias-arte-cultura/37-tendencia/517-barbara-kruger-o-el-poder-de-la-palabra" target="_blank" rel="noopener">BARBARA KRUGER OR THE POWER OF THE WORD<br />
</a></p>
<p><center><iframe loading="lazy" src="https://www.dur.ac.uk/scripts/rss/magpie/scripts/magpie_debug.php?url=http://appropriatemedia.net/feed" height="25" width="250" title=""></iframe></center></p>
";}s:7:"summary";s:546:"The American artist Barbara Kruger is a conceptual artist, who lives and works between Los Angeles and New York, right now she is working on one of the most important exhibitions on her career, which will be hosted in 2020 by the Art Institute of Chicago. Barbara Kruger&#8217;s work is one of the most recognized ... <a title="BARBARA KRUGER OR THE POWER OF THE WORD" class="read-more" href="https://celebritynews.fuzzyskunk.com/barbara-kruger-or-the-power-of-the-word/" aria-label="More on BARBARA KRUGER OR THE POWER OF THE WORD">Read more</a>";s:12:"atom_content";s:5137:"<div id="">
<p style="text-align: justify;">The American artist <strong>Barbara Kruger</strong> is a conceptual artist, who lives and works between Los Angeles and New York, right now she is working on one of the most important exhibitions on her career, which will be hosted in 2020 by the Art Institute of Chicago. <strong>Barbara Kruger&#8217;s work is one of the most recognized in contemporary art since the 70s, with her work she resorts to the power of the word, always questioning the established patterns and powers.</strong> His works are based on provocative phrases or comments that criticize the consumer society and indiscriminate abuses of power.</p>
<p style="text-align: justify;">Kruger&#8217;s work is impossible to understand without accepting the relationship he establishes between art and advertising, thus appropriating images from advertising media, cinema or television. <strong>In his work he proposes questions that today in the XXI century, we still have not been able to respond by addressing issues such as stereotyping, politics, the question of power, sexuality or representation.</strong> Following her training at Syracuse University (New York), she continued her career as a graphic designer, becoming chief designer at Mademoiselle magazine in New York.  In the 1960s and 1970s, she also explored her interest in poetry, inspired by Patty Smith and involved, in some way, with the feminist movement of the time.<strong> It was precisely at the end of the 70s, when Barbara Kruger began to establish a very clear line in her work. <br /></strong></p>
<p style="text-align: center;">
<p style="text-align: center;"><span style="font-size: 8pt;"> © Barbara Kruger</span></p>
<p style="text-align: justify;"><strong>  Through appropriate images, many of them in black and white, he introduces red, black or white text, which immediately provoke the viewer to react to an intelligent and direct approach that questions him about feminism, classism, consumerism, individual autonomy and desire. .  In his works we can find slogans such as: &#8220;Your body is a battleground&#8221; or &#8220;I shop therefore I am&#8221; (I buy, therefore I exist).  For Barbara Kruger, the woman is nothing other than a victim of a patriarchal system that objectifies her.  This is evident in his work made in 1989, entitled Untitled (Your Body is a Battleground), in which he uses a large image with the face of a model that he divides into sections.  In the image you can read the phrase &#8220;Your body is a battlefield&#8221;, thus questioning that objectification to which women are subjected and vindicating the reproductive rights of women.</strong></p>
</p>
<p style="text-align: center;"><strong><img src="http://www.madridartprocess.com/images/BARBARA-KRUGER-12.jpg" alt="BARBARA KRUGER 12" title="BARBARA KRUGER OR THE POWER OF THE WORD 2"></strong></p>
<p style="text-align: center;"><span style="font-size: 8pt;">© Barbara Kruger</span></p>
<p style="text-align: justify;">Barbara Kruger&#8217;s work is testament to the deconstructivist concerns that ran much of the feminist art of the 1980s and 1990s.  Influenced by writers such as Foucault, Baudrillard, Kristeva, Lacan and Derrida, she seeks to manipulate and recontextualize images, to question the way in which power represents female identity.  In 1975 her artistic work began to be different, acquiring a certain value of abstraction, a period of experimentation began, which led her to rethink her creative process and what it meant to ?call herself an artist?.  At the same time, his works were influenced by the work of artists such as Carol Squiers, Lynne Tillman, Rainer, Akerman or Mary Kelly.<strong> Already in the 80s, Kruger&#8217;s work became more popular after participating in Documenta VII, his work began to enter the commercial sphere of art.  This made the artist received criticism because she criticized the consumer society.  She has always defended saying that being part of the market meant being part of the gear, therefore more turned out to be a ploy to spread their message.  Within this context and exploring the relationship between space and violence, his work also appeared in museums and galleries around the world, where he proclaims his speech, has been on Billboards, posters, public parks, railway stations and other public places.</strong></p>
<p style="text-align: left;"><span style="color: #808080; font-size: 8pt;"><span style="color: #000000; font-family: arial black,sans-serif;"><strong>Eduardo Álvarez |  September 12, 2018</strong></span></span></p>
</p></div>
<p>We would like to  say thanks to the author of this  short article for this  remarkable  web content<br />
<br />
<a href="http://www.madridartprocess.com/tendencias-arte-cultura/37-tendencia/517-barbara-kruger-o-el-poder-de-la-palabra" target="_blank" rel="noopener">BARBARA KRUGER OR THE POWER OF THE WORD<br />
</a></p>
<p><center><iframe loading="lazy" src="https://www.dur.ac.uk/scripts/rss/magpie/scripts/magpie_debug.php?url=http://appropriatemedia.net/feed" height="25" width="250" title=""></iframe></center></p>
";s:14:"date_timestamp";i:1639796865;}i:2;a:11:{s:5:"title";s:32:"The origin of neuronal diversity";s:4:"link";s:70:"https://celebritynews.fuzzyskunk.com/the-origin-of-neuronal-diversity/";s:2:"dc";a:1:{s:7:"creator";s:12:"Tony Grantly";}s:7:"pubdate";s:31:"Sat, 18 Dec 2021 02:44:50 +0000";s:8:"category";s:41:"Health And SciencediversityneuronalOrigin";s:4:"guid";s:45:"https://celebritynews.fuzzyskunk.com/?p=19442";s:11:"description";s:612:"Journal Reference: Rachel C. Bandler, Ilaria Vitali, Ryan N. Delgado, May C. Ho, Elena Dvoretskova, Josue S. Ibarra Molinas, Paul W. Frazel, Maesoumeh Mohammadkhani, Robert Machold, Sophia Maedler, Shane A. Liddelow, Tomasz J. Nowakowski, Gord Fishell, Christian Mayer. Single-cell delineation of lineage and genetic identity in the mouse brain. Nature, 2021; DOI: 10.1038/s41586-021-04237-0 Our body ... <a title="The origin of neuronal diversity" class="read-more" href="https://celebritynews.fuzzyskunk.com/the-origin-of-neuronal-diversity/" aria-label="More on The origin of neuronal diversity">Read more</a>";s:7:"content";a:1:{s:7:"encoded";s:5336:"<div>
<p><strong>Journal Reference</strong>:</p>
<ol class="journal">
<li>Rachel C. Bandler, Ilaria Vitali, Ryan N. Delgado, May C. Ho, Elena Dvoretskova, Josue S. Ibarra Molinas, Paul W. Frazel, Maesoumeh Mohammadkhani, Robert Machold, Sophia Maedler, Shane A. Liddelow, Tomasz J. Nowakowski, Gord Fishell, Christian Mayer. <strong>Single-cell delineation of lineage and genetic identity in the mouse brain</strong>. Nature, 2021; DOI: <a rel="nofollow noopener" href="https://dx.doi.org/10.1038/s41586-021-04237-0" target="_blank">10.1038/s41586-021-04237-0</a>
</li>
</ol>
<p>Our body consists of hundreds of cell types, each with a very specific function. These cells can differ greatly in their properties ? which can be clearly seen by comparing, for example, a blood cell to a skin cell. Nevertheless, each cell carries identical genetic information. The diversity is possible because cells do not use all of this information. Each cell type only activates the genes that it actually requires. This subset is then translated into RNA and proteins, resulting in a very specific cell type.</p>
<p>The fate of most cells is determined during development. The process when unspecialized cells mature into specific cell types is called differentiation. Without differentiation, a fertilized egg cell could not give rise to an organism with different tissue types. Initially, the egg cell is capable of forming any cell type. In its descendant cells, this ability gradually decreases, so that towards the end of embryonic development, cells are usually only able to differentiate into one specific cell type.</p>
<p><strong>Large variety in the brain</strong></p>
<p>A particularly large variety of cell types is found in the brain, a majority of which are glial cells and neurons. These can be further divided into various specialized cell types: There are over 100 different types just for inhibitory neurons. They originate from neural progenitor cells that divide several times at the beginning of development. Later, their daughter cells give rise to the different cell types.</p>
<p>An unresolved question is still how this enormous diversity of cell types arises from undifferentiated progenitor cells within just a few weeks in humans or days in mouse. An international team led by Christian Mayer investigated the mechanisms that give rise to cell diversity in the mouse brain. The researchers were particularly interested whether different cell types can originate from a single progenitor cell, and at what time point during development the fate of the neurons becomes determined.</p>
<p><strong>Barcodes made of artificial DNA</strong></p>
<p>The scientists developed a new technique to label progenitor cells. To do so, they created millions of artificial DNA sequences, so-called barcodes. By inserting one of the barcodes in each cell, thousands of progenitor cells were uniquely marked ? similar to the barcodes we know used to scan consumer goods. When a labeled cell divided, it passed the barcode onto its daughter cells, making it possible to identify which cells descended from each other. The researchers combined this method with single-cell RNA sequencing, which identifies all active genes in a cell. Based on this information, they were able to classify the barcode-marked cells into different cell types.</p>
<p>By combining the two methods, the scientists showed that cell types and similarities between them cannot be used to make assumptions about developmental relationships: contrary to what is generally thought, cells of a similar cell type often cannot be traced back to a common origin in development. This means that unrelated progenitor cells can give rise to similar cell types (convergence).</p>
<p><strong>Different cell types from a single progenitor cell</strong></p>
<p>The scientists were also able to demonstrate the opposite scenario in inhibitory neurons: even different cell types in different brain structures can originate from the same progenitor cell (divergence). In this case, the progenitor cell seems to determine the neuron?s fate ? differentiation thus begins at the level of progenitor cells, and not later due to external signals. Accordingly, one progenitor cell can give rise to various neuronal cell types, and surprisingly until late in development ? a time point when it was assumed that this potential no longer existed.</p>
<p>The scientists expect that, based on these results, neurodevelopmental disorders will be better understood in the future. For example, examining the developmental relationships of cells could provide information about why certain groups of neurons are affected by genetic mutations that cause neurological and psychiatric illnesses. In addition, the novel method can be extended to any other tissue type, thus opening up an enormous spectrum of possible applications.</p>
</div>
<p>We  want to thank the author of this  write-up for this  outstanding  material<br />
<br />
<a href="https://novlink.co/the-origin-of-neuronal-diversity/" target="_blank" rel="noopener">The origin of neuronal diversity</a></p>
<p><center><iframe loading="lazy" src="http://www.spekulant.dk/news/scripts/magpie_slashbox.php?rss_url=http://feeds.feedburner.com/brandnewstores/caJG" height="25" width="250" title=""></iframe></center></p>
";}s:7:"summary";s:612:"Journal Reference: Rachel C. Bandler, Ilaria Vitali, Ryan N. Delgado, May C. Ho, Elena Dvoretskova, Josue S. Ibarra Molinas, Paul W. Frazel, Maesoumeh Mohammadkhani, Robert Machold, Sophia Maedler, Shane A. Liddelow, Tomasz J. Nowakowski, Gord Fishell, Christian Mayer. Single-cell delineation of lineage and genetic identity in the mouse brain. Nature, 2021; DOI: 10.1038/s41586-021-04237-0 Our body ... <a title="The origin of neuronal diversity" class="read-more" href="https://celebritynews.fuzzyskunk.com/the-origin-of-neuronal-diversity/" aria-label="More on The origin of neuronal diversity">Read more</a>";s:12:"atom_content";s:5336:"<div>
<p><strong>Journal Reference</strong>:</p>
<ol class="journal">
<li>Rachel C. Bandler, Ilaria Vitali, Ryan N. Delgado, May C. Ho, Elena Dvoretskova, Josue S. Ibarra Molinas, Paul W. Frazel, Maesoumeh Mohammadkhani, Robert Machold, Sophia Maedler, Shane A. Liddelow, Tomasz J. Nowakowski, Gord Fishell, Christian Mayer. <strong>Single-cell delineation of lineage and genetic identity in the mouse brain</strong>. Nature, 2021; DOI: <a rel="nofollow noopener" href="https://dx.doi.org/10.1038/s41586-021-04237-0" target="_blank">10.1038/s41586-021-04237-0</a>
</li>
</ol>
<p>Our body consists of hundreds of cell types, each with a very specific function. These cells can differ greatly in their properties ? which can be clearly seen by comparing, for example, a blood cell to a skin cell. Nevertheless, each cell carries identical genetic information. The diversity is possible because cells do not use all of this information. Each cell type only activates the genes that it actually requires. This subset is then translated into RNA and proteins, resulting in a very specific cell type.</p>
<p>The fate of most cells is determined during development. The process when unspecialized cells mature into specific cell types is called differentiation. Without differentiation, a fertilized egg cell could not give rise to an organism with different tissue types. Initially, the egg cell is capable of forming any cell type. In its descendant cells, this ability gradually decreases, so that towards the end of embryonic development, cells are usually only able to differentiate into one specific cell type.</p>
<p><strong>Large variety in the brain</strong></p>
<p>A particularly large variety of cell types is found in the brain, a majority of which are glial cells and neurons. These can be further divided into various specialized cell types: There are over 100 different types just for inhibitory neurons. They originate from neural progenitor cells that divide several times at the beginning of development. Later, their daughter cells give rise to the different cell types.</p>
<p>An unresolved question is still how this enormous diversity of cell types arises from undifferentiated progenitor cells within just a few weeks in humans or days in mouse. An international team led by Christian Mayer investigated the mechanisms that give rise to cell diversity in the mouse brain. The researchers were particularly interested whether different cell types can originate from a single progenitor cell, and at what time point during development the fate of the neurons becomes determined.</p>
<p><strong>Barcodes made of artificial DNA</strong></p>
<p>The scientists developed a new technique to label progenitor cells. To do so, they created millions of artificial DNA sequences, so-called barcodes. By inserting one of the barcodes in each cell, thousands of progenitor cells were uniquely marked ? similar to the barcodes we know used to scan consumer goods. When a labeled cell divided, it passed the barcode onto its daughter cells, making it possible to identify which cells descended from each other. The researchers combined this method with single-cell RNA sequencing, which identifies all active genes in a cell. Based on this information, they were able to classify the barcode-marked cells into different cell types.</p>
<p>By combining the two methods, the scientists showed that cell types and similarities between them cannot be used to make assumptions about developmental relationships: contrary to what is generally thought, cells of a similar cell type often cannot be traced back to a common origin in development. This means that unrelated progenitor cells can give rise to similar cell types (convergence).</p>
<p><strong>Different cell types from a single progenitor cell</strong></p>
<p>The scientists were also able to demonstrate the opposite scenario in inhibitory neurons: even different cell types in different brain structures can originate from the same progenitor cell (divergence). In this case, the progenitor cell seems to determine the neuron?s fate ? differentiation thus begins at the level of progenitor cells, and not later due to external signals. Accordingly, one progenitor cell can give rise to various neuronal cell types, and surprisingly until late in development ? a time point when it was assumed that this potential no longer existed.</p>
<p>The scientists expect that, based on these results, neurodevelopmental disorders will be better understood in the future. For example, examining the developmental relationships of cells could provide information about why certain groups of neurons are affected by genetic mutations that cause neurological and psychiatric illnesses. In addition, the novel method can be extended to any other tissue type, thus opening up an enormous spectrum of possible applications.</p>
</div>
<p>We  want to thank the author of this  write-up for this  outstanding  material<br />
<br />
<a href="https://novlink.co/the-origin-of-neuronal-diversity/" target="_blank" rel="noopener">The origin of neuronal diversity</a></p>
<p><center><iframe loading="lazy" src="http://www.spekulant.dk/news/scripts/magpie_slashbox.php?rss_url=http://feeds.feedburner.com/brandnewstores/caJG" height="25" width="250" title=""></iframe></center></p>
";s:14:"date_timestamp";i:1639795490;}i:3;a:11:{s:5:"title";s:37:"Marlene Dietrich, before being a myth";s:4:"link";s:74:"https://celebritynews.fuzzyskunk.com/marlene-dietrich-before-being-a-myth/";s:2:"dc";a:1:{s:7:"creator";s:12:"Sally Scully";}s:7:"pubdate";s:31:"Sat, 18 Dec 2021 01:53:05 +0000";s:8:"category";s:28:"CelebrityDietrichMarleneMyth";s:4:"guid";s:45:"https://celebritynews.fuzzyskunk.com/?p=19437";s:11:"description";s:529:"Isabel Peláez Madrid, June 30 (EFE) .- The collective retina has remained with his fine eyebrows, with his smoky and perennial cigar over his mouth, with his tuxedo and his top hat or with one of his films, but Marlene Dietrich was something more, or so a work by the writer Franz Hessel, translated for ... <a title="Marlene Dietrich, before being a myth" class="read-more" href="https://celebritynews.fuzzyskunk.com/marlene-dietrich-before-being-a-myth/" aria-label="More on Marlene Dietrich, before being a myth">Read more</a>";s:7:"content";a:1:{s:7:"encoded";s:5913:"<div>
<p data-gtm-element-container="modulo-texto-link" class="paragraph">Isabel Peláez</p>
<p data-gtm-element-container="modulo-texto-link" class="paragraph">Madrid, June 30 (EFE) .- The collective retina has remained with his fine eyebrows, with his smoky and perennial cigar over his mouth, with his tuxedo and his top hat or with one of his films, but Marlene Dietrich was something more, or so a work by the writer Franz Hessel, translated for the first time into Spanish, tries to show it.</p>
<p data-gtm-element-container="modulo-texto-link" class="paragraph">&#8220;Marlene Dietrich&#8221; (Errata Naturae) was born in 1931, when Berlin was still a city full of light and possibilities, so Hessel&#8217;s early portrait of the actress is outlined with the happiest moments of a budding icon, already known for her appearance in films such as &#8220;The Blue Angel&#8221; (1930), her springboard to fame, but not yet consecrated as a world cinema diva.</p>
<p><span class="content-ad-module  hidden-ad"></p>
<p><span class="content-ad visible-xs roba-container  hidden-ad"><span class="ad-unit roba"></p>
<p>                </span></span><span class="content-ad visible-md irr-container  hidden-ad"><span class="ad-unit irr"></p>
<p>                </span></span><span class="content-html"><span class="intext-md hidden-xs hidden-md"/></span></span></p>
<p data-gtm-element-container="modulo-texto-link" class="paragraph">&#8220;Marlene Dietrich always gives life to a universal dream, like the heroine of one of her films, she is the woman that everyone wants; everyone, not this one or that one, but each one, the people, the world, the time&#8221;, describes Franz Hessel in this short biography written when the artist was still on the verge of success.</p>
<p data-gtm-element-container="modulo-texto-link" class="paragraph">&#8220;La Dietrich&#8221; was not born a myth, as no myth is born, but is made, and her fame was preceded by an arduous training in music &#8211; she played the piano and violin &#8211; and in interpretation, &#8220;that is what Hessel emphasizes in his text, the preparation of an artist whom some considered a mere product of American advertising &#8220;, Irene Antón, editor of Errata Naturae, explains to Efe.</p>
<p data-gtm-element-container="modulo-texto-link" class="paragraph">The book, almost a love poem, is a waste of lyricism turned into a plea, since Hessel defends Marlene Dietrich from the evil tongues that, at that time, tried to vilify her &#8220;undoubted&#8221; talent for the cinema, to which she arrived with a certain background thanks to his work in the theater and in the cabaret, where his &#8220;tomboy&#8221; style of trousers, shirts and ties became the chair.</p>
<p data-gtm-element-container="modulo-texto-link" class="paragraph">At the time Hessel wrote &#8220;Marlene Dietrich&#8221;, Nazism had not yet stifled the scent of freedom that was breathed in the Berlin of the 1920s;  With the establishment of the Third Reich, the artist and the writer went into exile;  she for being a confessed opponent of that form of state, and he for being a Jew.</p>
<p><span class="content-ad-module  hidden-ad"></p>
<p><span class="content-ad visible-xs irr-container  hidden-ad"><span class="ad-unit irr"></p>
<p>                </span></span><span class="content-html"><span class="intext-xs hidden-xs hidden-md"/></span></span></p>
<p data-gtm-element-container="modulo-texto-link" class="paragraph">&#8220;Marlene&#8217;s ability to fight for what she believed in&#8221;, considers Antón, was what sparked the admiration of Franz Hessel, a born observer capable of grasping reality and turning it into a &#8220;magical&#8221; and subtle story, a man &#8220;that he tried to understand what he saw, not to possess it&#8221;, justifies the editor.</p>
<p data-gtm-element-container="modulo-texto-link" class="paragraph">The images provided by Hessel&#8217;s little book, who sometimes dedicates to &#8220;the Dietrich&#8221; a few words almost like an infant in love, provide a double drawing of who that blonde, magnetic and passionate woman was, &#8220;someone with an important emotional intelligence that It made me have my feet on the ground, &#8220;explains Antón.</p>
<p data-gtm-element-container="modulo-texto-link" class="paragraph">But behind that determination that the actress of &#8220;Morocco&#8221; (1930) almost always showed, the only film that earned her an Oscar nomination, or of &#8220;The Shanghai Express&#8221; (1932), the girl with the bow tie who was not afraid Teaching the garter belt in one of her dances, a contemporary of another divine, Greta Garbo, had a weakness with her own name: María Riva, her daughter.</p>
<p data-gtm-element-container="modulo-texto-link" class="paragraph">In the only meeting with Marlene Dietrich that Franz Hessel describes in the book, a passage full of intimacy, the artist told the writer and translator: &#8220;If you consider it appropriate to tell people about my private life, then please tell them that she (for her daughter) is the most important thing, she is the reason for my life &#8220;.</p>
<p><span class="content-ad-module  hidden-ad"></p>
<p><span class="content-ad visible-xs roba-container  hidden-ad"><span class="ad-unit roba"></p>
<p>                </span></span></span></p>
<p data-gtm-element-container="modulo-texto-link" class="paragraph">ip/cr</p>
</div>
<p>We  want to thank the  writer of this  post for this awesome  web content<br />
<br />
<a href="https://www.lavanguardia.com/gente/20140630/54410562640/marlene-dietrich-antes-de-ser-un-mito.html" target="_blank" rel="noopener">Marlene Dietrich, before being a myth<br />
</a></p>
<p><center><iframe loading="lazy" src="https://www.neildouglas.co.uk/magpierss/scripts/magpie_debug.php?url=http://innovativenews.xyz/" height="25" width="250" title=""></iframe></center></p>
";}s:7:"summary";s:529:"Isabel Peláez Madrid, June 30 (EFE) .- The collective retina has remained with his fine eyebrows, with his smoky and perennial cigar over his mouth, with his tuxedo and his top hat or with one of his films, but Marlene Dietrich was something more, or so a work by the writer Franz Hessel, translated for ... <a title="Marlene Dietrich, before being a myth" class="read-more" href="https://celebritynews.fuzzyskunk.com/marlene-dietrich-before-being-a-myth/" aria-label="More on Marlene Dietrich, before being a myth">Read more</a>";s:12:"atom_content";s:5913:"<div>
<p data-gtm-element-container="modulo-texto-link" class="paragraph">Isabel Peláez</p>
<p data-gtm-element-container="modulo-texto-link" class="paragraph">Madrid, June 30 (EFE) .- The collective retina has remained with his fine eyebrows, with his smoky and perennial cigar over his mouth, with his tuxedo and his top hat or with one of his films, but Marlene Dietrich was something more, or so a work by the writer Franz Hessel, translated for the first time into Spanish, tries to show it.</p>
<p data-gtm-element-container="modulo-texto-link" class="paragraph">&#8220;Marlene Dietrich&#8221; (Errata Naturae) was born in 1931, when Berlin was still a city full of light and possibilities, so Hessel&#8217;s early portrait of the actress is outlined with the happiest moments of a budding icon, already known for her appearance in films such as &#8220;The Blue Angel&#8221; (1930), her springboard to fame, but not yet consecrated as a world cinema diva.</p>
<p><span class="content-ad-module  hidden-ad"></p>
<p><span class="content-ad visible-xs roba-container  hidden-ad"><span class="ad-unit roba"></p>
<p>                </span></span><span class="content-ad visible-md irr-container  hidden-ad"><span class="ad-unit irr"></p>
<p>                </span></span><span class="content-html"><span class="intext-md hidden-xs hidden-md"/></span></span></p>
<p data-gtm-element-container="modulo-texto-link" class="paragraph">&#8220;Marlene Dietrich always gives life to a universal dream, like the heroine of one of her films, she is the woman that everyone wants; everyone, not this one or that one, but each one, the people, the world, the time&#8221;, describes Franz Hessel in this short biography written when the artist was still on the verge of success.</p>
<p data-gtm-element-container="modulo-texto-link" class="paragraph">&#8220;La Dietrich&#8221; was not born a myth, as no myth is born, but is made, and her fame was preceded by an arduous training in music &#8211; she played the piano and violin &#8211; and in interpretation, &#8220;that is what Hessel emphasizes in his text, the preparation of an artist whom some considered a mere product of American advertising &#8220;, Irene Antón, editor of Errata Naturae, explains to Efe.</p>
<p data-gtm-element-container="modulo-texto-link" class="paragraph">The book, almost a love poem, is a waste of lyricism turned into a plea, since Hessel defends Marlene Dietrich from the evil tongues that, at that time, tried to vilify her &#8220;undoubted&#8221; talent for the cinema, to which she arrived with a certain background thanks to his work in the theater and in the cabaret, where his &#8220;tomboy&#8221; style of trousers, shirts and ties became the chair.</p>
<p data-gtm-element-container="modulo-texto-link" class="paragraph">At the time Hessel wrote &#8220;Marlene Dietrich&#8221;, Nazism had not yet stifled the scent of freedom that was breathed in the Berlin of the 1920s;  With the establishment of the Third Reich, the artist and the writer went into exile;  she for being a confessed opponent of that form of state, and he for being a Jew.</p>
<p><span class="content-ad-module  hidden-ad"></p>
<p><span class="content-ad visible-xs irr-container  hidden-ad"><span class="ad-unit irr"></p>
<p>                </span></span><span class="content-html"><span class="intext-xs hidden-xs hidden-md"/></span></span></p>
<p data-gtm-element-container="modulo-texto-link" class="paragraph">&#8220;Marlene&#8217;s ability to fight for what she believed in&#8221;, considers Antón, was what sparked the admiration of Franz Hessel, a born observer capable of grasping reality and turning it into a &#8220;magical&#8221; and subtle story, a man &#8220;that he tried to understand what he saw, not to possess it&#8221;, justifies the editor.</p>
<p data-gtm-element-container="modulo-texto-link" class="paragraph">The images provided by Hessel&#8217;s little book, who sometimes dedicates to &#8220;the Dietrich&#8221; a few words almost like an infant in love, provide a double drawing of who that blonde, magnetic and passionate woman was, &#8220;someone with an important emotional intelligence that It made me have my feet on the ground, &#8220;explains Antón.</p>
<p data-gtm-element-container="modulo-texto-link" class="paragraph">But behind that determination that the actress of &#8220;Morocco&#8221; (1930) almost always showed, the only film that earned her an Oscar nomination, or of &#8220;The Shanghai Express&#8221; (1932), the girl with the bow tie who was not afraid Teaching the garter belt in one of her dances, a contemporary of another divine, Greta Garbo, had a weakness with her own name: María Riva, her daughter.</p>
<p data-gtm-element-container="modulo-texto-link" class="paragraph">In the only meeting with Marlene Dietrich that Franz Hessel describes in the book, a passage full of intimacy, the artist told the writer and translator: &#8220;If you consider it appropriate to tell people about my private life, then please tell them that she (for her daughter) is the most important thing, she is the reason for my life &#8220;.</p>
<p><span class="content-ad-module  hidden-ad"></p>
<p><span class="content-ad visible-xs roba-container  hidden-ad"><span class="ad-unit roba"></p>
<p>                </span></span></span></p>
<p data-gtm-element-container="modulo-texto-link" class="paragraph">ip/cr</p>
</div>
<p>We  want to thank the  writer of this  post for this awesome  web content<br />
<br />
<a href="https://www.lavanguardia.com/gente/20140630/54410562640/marlene-dietrich-antes-de-ser-un-mito.html" target="_blank" rel="noopener">Marlene Dietrich, before being a myth<br />
</a></p>
<p><center><iframe loading="lazy" src="https://www.neildouglas.co.uk/magpierss/scripts/magpie_debug.php?url=http://innovativenews.xyz/" height="25" width="250" title=""></iframe></center></p>
";s:14:"date_timestamp";i:1639792385;}i:4;a:11:{s:5:"title";s:74:"Kim Jong-un celebrates ten years in power in a country closed in on itself";s:4:"link";s:112:"https://celebritynews.fuzzyskunk.com/kim-jong-un-celebrates-ten-years-in-power-in-a-country-closed-in-on-itself/";s:2:"dc";a:1:{s:7:"creator";s:12:"Susan Qnenly";}s:7:"pubdate";s:31:"Sat, 18 Dec 2021 01:51:37 +0000";s:8:"category";s:47:"World NewsCelebratesclosedcountryJongunKimpower";s:4:"guid";s:45:"https://celebritynews.fuzzyskunk.com/?p=19431";s:11:"description";s:641:"Photos of North Korean leaders Kim Il-sung and Kim Jong-il, in Pyongyang, December 3, 2018. ED JONES / AFP When he was thrown to the top of the Democratic People&#8217;s Republic of Korea (DPRK) the day after the sudden death of his father Kim Jong-il on December 17, 2011, Kim Jong-un was 27 years old. ... <a title="Kim Jong-un celebrates ten years in power in a country closed in on itself" class="read-more" href="https://celebritynews.fuzzyskunk.com/kim-jong-un-celebrates-ten-years-in-power-in-a-country-closed-in-on-itself/" aria-label="More on Kim Jong-un celebrates ten years in power in a country closed in on itself">Read more</a>";s:7:"content";a:1:{s:7:"encoded";s:4412:"<div id="">
<figure class="article__media">  <noscript> <img src="https://img.lemde.fr/2021/12/17/0/0/7303/4874/664/0/75/0/e8e0155_861100216-457754.jpg" alt="Photos of North Korean leaders Kim Il-sung and Kim Jong-il, in Pyongyang, December 3, 2018." title="Kim Jong-un celebrates ten years in power in a country closed in on itself 4"> </noscript><figcaption class="article__legend" aria-hidden="true">Photos of North Korean leaders Kim Il-sung and Kim Jong-il, in Pyongyang, December 3, 2018. <span class="article__credit" aria-hidden="true">ED JONES / AFP</span> </figcaption></figure>
<p class="article__paragraph ">When he was thrown to the top of the Democratic People&#8217;s Republic of Korea (DPRK) the day after the sudden death of his father Kim Jong-il on December 17, 2011, Kim Jong-un was 27 years old.  We could then doubt his ability to control the most monolithic regime on the planet.  Officially appointed the previous year as the future ruler, he had no experience of power;  he was not even a member of the political bureau of the Labor Party, the political formation of the regime.</p>
<p class="article__paragraph ">The second dynastic succession of the communist world risked being less easy than the previous one, when Kim Jong-un had succeeded in 1994 to his father Kim Il-sun, founder of the DPRK.  A military coup, if not the collapse of the regime, was <em>&#8220;A matter of weeks or months&#8221;,</em> thus argued Victor Cha, former adviser for Asian affairs at the White House.  Even if he was not ousted, the &#8220;great successor&#8221; seemed, at best, to be destined to find himself under the tutelage of a council of regency.</p>
<p class="article__paragraph ">Ten years later, the regime is still there, and Kim Jong-un has not only survived: he has an undisputed authority, haloed at the beginning of 2021 with the title of &#8220;Great Leader&#8221;, placing him on the same rank as his. ancestors.  And he has imposed his presence on the international scene by making his country a nuclear power &#8211; even if it is not recognized as such.</p>
<p class="article__paragraph ">With a volley of ballistic missiles and three new atomic tests, the last of which, in 2017, finalized North Korea&#8217;s entry into the club of nuclear powers, the DPRK is seen as a direct threat by the United States and their allies.  The Security Council (which includes China and Russia) tightened economic sanctions against the country already.  Then, after invectives and reciprocal threats of annihilation of Pyongyang and Washington, the storm settled.</p>
<h2 class="article__sub-title">Annoyed rapprochement</h2>
<p class="article__paragraph ">The Winter Olympics in Pyeongchang (February 2018) in South Korea indeed consecrated the inter-Korean rapprochement and allowed President Moon Jae-in to initiate a dialogue between the United States and the DPRK, which led to a first summit in Singapore (June 2018) between President Donald Trump and Kim Jong-un.  The second, organized in Hanoi (February 2019), was cut short: Mr. Kim&#8217;s offer to shut down the (dilapidated) Yongbyon nuclear power plant, in exchange for the lifting of UN sanctions, was deemed insufficient. by Washington.</p>
<p class="article__paragraph ">After these two meetings with the President of the United States, sworn enemy of the regime, Kim Jong-un managed to impose his massive figure and his youthful face on the international scene.  &#8220;Rocket Man&#8221;<em>,</em> as Donald Trump nicknamed him, achieved the goal of his predecessors: to force Washington to recognize the DPRK as a power the world must reckon with &#8211; and to negotiate.</p>
<p><strong>You have 67.52% of this article left to read.  The rest is for subscribers only.</strong></p>
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<p>We  want to  say thanks to the author of this  write-up for this  amazing content<br />
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</a></p>
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";}s:7:"summary";s:641:"Photos of North Korean leaders Kim Il-sung and Kim Jong-il, in Pyongyang, December 3, 2018. ED JONES / AFP When he was thrown to the top of the Democratic People&#8217;s Republic of Korea (DPRK) the day after the sudden death of his father Kim Jong-il on December 17, 2011, Kim Jong-un was 27 years old. ... <a title="Kim Jong-un celebrates ten years in power in a country closed in on itself" class="read-more" href="https://celebritynews.fuzzyskunk.com/kim-jong-un-celebrates-ten-years-in-power-in-a-country-closed-in-on-itself/" aria-label="More on Kim Jong-un celebrates ten years in power in a country closed in on itself">Read more</a>";s:12:"atom_content";s:4412:"<div id="">
<figure class="article__media">  <noscript> <img src="https://img.lemde.fr/2021/12/17/0/0/7303/4874/664/0/75/0/e8e0155_861100216-457754.jpg" alt="Photos of North Korean leaders Kim Il-sung and Kim Jong-il, in Pyongyang, December 3, 2018." title="Kim Jong-un celebrates ten years in power in a country closed in on itself 4"> </noscript><figcaption class="article__legend" aria-hidden="true">Photos of North Korean leaders Kim Il-sung and Kim Jong-il, in Pyongyang, December 3, 2018. <span class="article__credit" aria-hidden="true">ED JONES / AFP</span> </figcaption></figure>
<p class="article__paragraph ">When he was thrown to the top of the Democratic People&#8217;s Republic of Korea (DPRK) the day after the sudden death of his father Kim Jong-il on December 17, 2011, Kim Jong-un was 27 years old.  We could then doubt his ability to control the most monolithic regime on the planet.  Officially appointed the previous year as the future ruler, he had no experience of power;  he was not even a member of the political bureau of the Labor Party, the political formation of the regime.</p>
<p class="article__paragraph ">The second dynastic succession of the communist world risked being less easy than the previous one, when Kim Jong-un had succeeded in 1994 to his father Kim Il-sun, founder of the DPRK.  A military coup, if not the collapse of the regime, was <em>&#8220;A matter of weeks or months&#8221;,</em> thus argued Victor Cha, former adviser for Asian affairs at the White House.  Even if he was not ousted, the &#8220;great successor&#8221; seemed, at best, to be destined to find himself under the tutelage of a council of regency.</p>
<p class="article__paragraph ">Ten years later, the regime is still there, and Kim Jong-un has not only survived: he has an undisputed authority, haloed at the beginning of 2021 with the title of &#8220;Great Leader&#8221;, placing him on the same rank as his. ancestors.  And he has imposed his presence on the international scene by making his country a nuclear power &#8211; even if it is not recognized as such.</p>
<p class="article__paragraph ">With a volley of ballistic missiles and three new atomic tests, the last of which, in 2017, finalized North Korea&#8217;s entry into the club of nuclear powers, the DPRK is seen as a direct threat by the United States and their allies.  The Security Council (which includes China and Russia) tightened economic sanctions against the country already.  Then, after invectives and reciprocal threats of annihilation of Pyongyang and Washington, the storm settled.</p>
<h2 class="article__sub-title">Annoyed rapprochement</h2>
<p class="article__paragraph ">The Winter Olympics in Pyeongchang (February 2018) in South Korea indeed consecrated the inter-Korean rapprochement and allowed President Moon Jae-in to initiate a dialogue between the United States and the DPRK, which led to a first summit in Singapore (June 2018) between President Donald Trump and Kim Jong-un.  The second, organized in Hanoi (February 2019), was cut short: Mr. Kim&#8217;s offer to shut down the (dilapidated) Yongbyon nuclear power plant, in exchange for the lifting of UN sanctions, was deemed insufficient. by Washington.</p>
<p class="article__paragraph ">After these two meetings with the President of the United States, sworn enemy of the regime, Kim Jong-un managed to impose his massive figure and his youthful face on the international scene.  &#8220;Rocket Man&#8221;<em>,</em> as Donald Trump nicknamed him, achieved the goal of his predecessors: to force Washington to recognize the DPRK as a power the world must reckon with &#8211; and to negotiate.</p>
<p><strong>You have 67.52% of this article left to read.  The rest is for subscribers only.</strong></p>
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</a></p>
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";s:14:"date_timestamp";i:1639792297;}i:5;a:11:{s:5:"title";s:115:"Grandmother, daughter and granddaughters: female ?gang? resumes her career after leaving prison.  were caught again";s:4:"link";s:147:"https://celebritynews.fuzzyskunk.com/grandmother-daughter-and-granddaughters-female-gang-resumes-her-career-after-leaving-prison-were-caught-again/";s:2:"dc";a:1:{s:7:"creator";s:12:"Paula Hooper";}s:7:"pubdate";s:31:"Sat, 18 Dec 2021 01:46:49 +0000";s:8:"category";s:83:"MagazinecareercaughtDaughterFemaleganggranddaughtersgrandmotherLeavingprisonresumes";s:4:"guid";s:45:"https://celebritynews.fuzzyskunk.com/?p=19425";s:11:"description";s:805:"A group of Colombian pickpockets, consisting of a grandmother, daughter and granddaughters, resumed a fruitful career dedicated to crime after being convicted by the courts in 2017. Now they have been caught again. Today septuagenarian, the matriarch who leads the gang, and lives in a condominium in the municipality of Palmela with her husband, she ... <a title="Grandmother, daughter and granddaughters: female ?gang? resumes her career after leaving prison.  were caught again" class="read-more" href="https://celebritynews.fuzzyskunk.com/grandmother-daughter-and-granddaughters-female-gang-resumes-her-career-after-leaving-prison-were-caught-again/" aria-label="More on Grandmother, daughter and granddaughters: female ?gang? resumes her career after leaving prison.  were caught again">Read more</a>";s:7:"content";a:1:{s:7:"encoded";s:5719:"<div data-ad-slots="11" id="story-body" data-io-article-url="https://www.publico.pt/2021/12/17/sociedade/noticia/avo-filha-netas-gang-feminino-retoma-carreira-sair-cadeia-apanhadas-1989077">
<p>A group of Colombian pickpockets, consisting of a grandmother, daughter and granddaughters, resumed a fruitful career dedicated to crime after being convicted by the courts in 2017. Now they have been caught again.</p>
<aside class="ad-slot ad-slot--in-content  incontent-hidden"/>
<p>Today septuagenarian, the matriarch who leads the <em>gang,</em> and lives in a condominium in the municipality of Palmela with her husband, she rented a safe at the bank to hide necklaces, rings and other pieces in gold and jewelry worth more than 46 thousand euros the first time she attracted the attention of authorities.  At the time, he and his descendants ? a daughter, three granddaughters and a niece ? were dedicated to the so-called luxury segment.  In his home and in the apartments of his relatives, also located on the South Bank, an impressive number of Louis Vuitton, Dior, Gucci, Burberry, Moschino, Guess and Carolina Herrera suitcases and wallets, among other brands, were discovered.</p>
<p>They attacked middle-aged or elderly women strolling through shopping centers.  They watched them use the code on the cards at the ATM machine and followed them until there was an opportunity to get close enough, either while paying for purchases in a store or at the revolving door of a commercial space.  Well dressed and carefully coiffed, they aroused no suspicion when approaching their victims.  As if by magical arts, stuffed leather wallets and the payment cards that lived inside were passed from the bags of the legitimate owners into their hands.</p>
<p>To facilitate the disappearance of the thieves in the crowd, while some fled, others started conversations with the victims, who thus took longer to notice the theft.  In police jargon, whoever stays behind to cover up his accomplices is ?giving himself to death?.</p>
<p>Won plate, worn plate: in possession of the codes on the cards, which they had managed to keep tabs on the victims while they raised money, frequented casinos and bought expensive perfumes, <em>gadgets</em> technological and whatever they liked best.  A police source said they were shopping addicts.</p>
<aside class="ad-slot ad-slot--double show-for-large"/>
<aside class="ad-slot ad-slot--sticky show-for-small"/>
<p>The PSP, which investigated the case, dubbed them Manitas de Plata, in honor of a Gypsy guitarist who has become a world celebrity.  In April 2017, it was thought that the Portuguese justice system had ended his career, by decreeing effective prison sentences for three of the women and suspended sentences for the others.  But after all, no.  After being released &#8211; some on precarious freedom, others thanks to the leniency regime motivated by the pandemic &#8211; they returned to action, now with more family members.</p>
<p>For at least a year, the gang headed by the matriarch has returned to work across the country, as in the past, to the point where the attention of the police was aroused because ?theft of wallets in supermarkets, centers is on the national level. commercial and other stores, all of which are associated with cash withdrawals and payments made with bank cards arising from these thefts?.</p>
<p>It was precisely with a theft in a supermarket in the municipality of Amadora that the new investigations began.  The PSP has gathered information over the last year that links the gang ? which also includes a son of the matriarch ? to 30 wallet thefts and 13 computer scams related to cash withdrawals and payments with stolen cards.  The value of the total damage caused to the victims is around 21,500 euros</p>
<p>Last Monday, the police mounted an operation which this time called Feliz Navidad, having witnessed the moment when three of the women took possession of an elderly woman&#8217;s wallet, inside a commercial establishment.  Then they raised 400 euros (200 at a time) at an ATM machine, fleeing the scene by car.  The leader, Myriam Muñoz, also followed in the vehicle.</p>
<aside class="ad-slot ad-slot--sticky show-for-large"/>
<aside class="ad-slot ad-slot--sticky show-for-small"/>
<p>?They ended up being detained, safely, in the Costa da Caparica area?, describes the PSP.  ?At the time of arrest, the mobile phone and bank card that had been stolen moments before, as well as all the money from the theft and bank withdrawals, were seized.  It was even possible to recover the old woman&#8217;s wallet that had been thrown away by pickpockets right after the theft?, also describes the same press release.</p>
<p>After that two other accomplices were also arrested.  Four of them, including septuagenarian, were ordered in preventive detention.  The Criminal Investigation Division of the PSP in Lisbon will continue to work on this case, as the investigation of responsibilities has not ended.</p>
<aside class="ad-slot ad-slot--double show-for-small"/>
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<p>We  want to  give thanks to the author of this  write-up for this  amazing content<br />
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<a href="https://www.publico.pt/2021/12/17/sociedade/noticia/avo-filha-netas-gang-feminino-retoma-carreira-sair-cadeia-apanhadas-1989077" target="_blank" rel="noopener"> Grandmother, daughter and granddaughters: female ?gang? resumes her career after leaving prison.  were caught again<br />
</a></p>
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";}s:7:"summary";s:805:"A group of Colombian pickpockets, consisting of a grandmother, daughter and granddaughters, resumed a fruitful career dedicated to crime after being convicted by the courts in 2017. Now they have been caught again. Today septuagenarian, the matriarch who leads the gang, and lives in a condominium in the municipality of Palmela with her husband, she ... <a title="Grandmother, daughter and granddaughters: female ?gang? resumes her career after leaving prison.  were caught again" class="read-more" href="https://celebritynews.fuzzyskunk.com/grandmother-daughter-and-granddaughters-female-gang-resumes-her-career-after-leaving-prison-were-caught-again/" aria-label="More on Grandmother, daughter and granddaughters: female ?gang? resumes her career after leaving prison.  were caught again">Read more</a>";s:12:"atom_content";s:5719:"<div data-ad-slots="11" id="story-body" data-io-article-url="https://www.publico.pt/2021/12/17/sociedade/noticia/avo-filha-netas-gang-feminino-retoma-carreira-sair-cadeia-apanhadas-1989077">
<p>A group of Colombian pickpockets, consisting of a grandmother, daughter and granddaughters, resumed a fruitful career dedicated to crime after being convicted by the courts in 2017. Now they have been caught again.</p>
<aside class="ad-slot ad-slot--in-content  incontent-hidden"/>
<p>Today septuagenarian, the matriarch who leads the <em>gang,</em> and lives in a condominium in the municipality of Palmela with her husband, she rented a safe at the bank to hide necklaces, rings and other pieces in gold and jewelry worth more than 46 thousand euros the first time she attracted the attention of authorities.  At the time, he and his descendants ? a daughter, three granddaughters and a niece ? were dedicated to the so-called luxury segment.  In his home and in the apartments of his relatives, also located on the South Bank, an impressive number of Louis Vuitton, Dior, Gucci, Burberry, Moschino, Guess and Carolina Herrera suitcases and wallets, among other brands, were discovered.</p>
<p>They attacked middle-aged or elderly women strolling through shopping centers.  They watched them use the code on the cards at the ATM machine and followed them until there was an opportunity to get close enough, either while paying for purchases in a store or at the revolving door of a commercial space.  Well dressed and carefully coiffed, they aroused no suspicion when approaching their victims.  As if by magical arts, stuffed leather wallets and the payment cards that lived inside were passed from the bags of the legitimate owners into their hands.</p>
<p>To facilitate the disappearance of the thieves in the crowd, while some fled, others started conversations with the victims, who thus took longer to notice the theft.  In police jargon, whoever stays behind to cover up his accomplices is ?giving himself to death?.</p>
<p>Won plate, worn plate: in possession of the codes on the cards, which they had managed to keep tabs on the victims while they raised money, frequented casinos and bought expensive perfumes, <em>gadgets</em> technological and whatever they liked best.  A police source said they were shopping addicts.</p>
<aside class="ad-slot ad-slot--double show-for-large"/>
<aside class="ad-slot ad-slot--sticky show-for-small"/>
<p>The PSP, which investigated the case, dubbed them Manitas de Plata, in honor of a Gypsy guitarist who has become a world celebrity.  In April 2017, it was thought that the Portuguese justice system had ended his career, by decreeing effective prison sentences for three of the women and suspended sentences for the others.  But after all, no.  After being released &#8211; some on precarious freedom, others thanks to the leniency regime motivated by the pandemic &#8211; they returned to action, now with more family members.</p>
<p>For at least a year, the gang headed by the matriarch has returned to work across the country, as in the past, to the point where the attention of the police was aroused because ?theft of wallets in supermarkets, centers is on the national level. commercial and other stores, all of which are associated with cash withdrawals and payments made with bank cards arising from these thefts?.</p>
<p>It was precisely with a theft in a supermarket in the municipality of Amadora that the new investigations began.  The PSP has gathered information over the last year that links the gang ? which also includes a son of the matriarch ? to 30 wallet thefts and 13 computer scams related to cash withdrawals and payments with stolen cards.  The value of the total damage caused to the victims is around 21,500 euros</p>
<p>Last Monday, the police mounted an operation which this time called Feliz Navidad, having witnessed the moment when three of the women took possession of an elderly woman&#8217;s wallet, inside a commercial establishment.  Then they raised 400 euros (200 at a time) at an ATM machine, fleeing the scene by car.  The leader, Myriam Muñoz, also followed in the vehicle.</p>
<aside class="ad-slot ad-slot--sticky show-for-large"/>
<aside class="ad-slot ad-slot--sticky show-for-small"/>
<p>?They ended up being detained, safely, in the Costa da Caparica area?, describes the PSP.  ?At the time of arrest, the mobile phone and bank card that had been stolen moments before, as well as all the money from the theft and bank withdrawals, were seized.  It was even possible to recover the old woman&#8217;s wallet that had been thrown away by pickpockets right after the theft?, also describes the same press release.</p>
<p>After that two other accomplices were also arrested.  Four of them, including septuagenarian, were ordered in preventive detention.  The Criminal Investigation Division of the PSP in Lisbon will continue to work on this case, as the investigation of responsibilities has not ended.</p>
<aside class="ad-slot ad-slot--double show-for-small"/>
            </div>
<p>We  want to  give thanks to the author of this  write-up for this  amazing content<br />
<br />
<a href="https://www.publico.pt/2021/12/17/sociedade/noticia/avo-filha-netas-gang-feminino-retoma-carreira-sair-cadeia-apanhadas-1989077" target="_blank" rel="noopener"> Grandmother, daughter and granddaughters: female ?gang? resumes her career after leaving prison.  were caught again<br />
</a></p>
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";s:14:"date_timestamp";i:1639792009;}i:6;a:11:{s:5:"title";s:88:"The most romantic photos of Orlando Bloom and Katy Perry during their vacation in Venice";s:4:"link";s:126:"https://celebritynews.fuzzyskunk.com/the-most-romantic-photos-of-orlando-bloom-and-katy-perry-during-their-vacation-in-venice/";s:2:"dc";a:1:{s:7:"creator";s:10:"Tom Pauler";}s:7:"pubdate";s:31:"Sat, 18 Dec 2021 01:40:37 +0000";s:8:"category";s:58:"CelebritybloomKatyOrlandoPerryPhotosromanticvacationVenice";s:4:"guid";s:45:"https://celebritynews.fuzzyskunk.com/?p=19420";s:11:"description";s:666:"Orlando Bloom and Katy Perry enjoy some well deserved vacation with daughter Daisy Dove. The actor of Pirates of the Caribbean and the singer of Electric have traveled to Italy to spend a few days off in one of the most romantic cities in the world built on a lagoon in the north of the ... <a title="The most romantic photos of Orlando Bloom and Katy Perry during their vacation in Venice" class="read-more" href="https://celebritynews.fuzzyskunk.com/the-most-romantic-photos-of-orlando-bloom-and-katy-perry-during-their-vacation-in-venice/" aria-label="More on The most romantic photos of Orlando Bloom and Katy Perry during their vacation in Venice">Read more</a>";s:7:"content";a:1:{s:7:"encoded";s:7150:"<div id="containerIntextAd">
<p>                <!-- ## MOBILE ROBAPAGINAS --></p>
<p>Orlando Bloom and Katy Perry enjoy some<strong> well deserved vacation with daughter Daisy Dove</strong>.  The actor of <em>Pirates of the Caribbean</em> and the singer of<em> Electric</em> have traveled to Italy to spend a few days off in <strong>one of the most romantic cities in the world</strong> built on a lagoon in the north of the Adriatic Sea.  Gondola rides, photos under the Bridge of Sighs or most pleasant moments with your daughter in the vicinity of the well-known St. Mark&#8217;s Square have not been lacking in your visit through the incomparable and narrow alleys of the magical and monumental Venice.</p>
<p><strong>-The funny video of Katy Perry &#8216;sneaking&#8217; into Orlando Bloom&#8217;s pose</strong></p>
<p>        <img loading="lazy" alt="Katy Perry" itemprop="url" src="https://www.hola.com/imagenes/actualidad/20210617191604/orland-bloom-katy-perry-vacaciones-venecia/0-965-353/orlando-bloom5-a.jpg" width="auto" height="auto" title="The most romantic photos of Orlando Bloom and Katy Perry during their vacation in Venice 9"><span>VIEW GALLERY<i data-icon="1" class="icon"/></span><br />
        <span class="copyright" data-copy="© katyperry"/><br />
        <meta itemprop="width" content="auto"/><meta itemprop="height" content="auto"/>
</p>
<p>        <img loading="lazy" alt="Katy Perry" itemprop="url" src="https://www.hola.com/imagenes/actualidad/20210617191604/orland-bloom-katy-perry-vacaciones-venecia/0-965-351/orlando-bloom4-a.jpg" width="auto" height="auto" title="The most romantic photos of Orlando Bloom and Katy Perry during their vacation in Venice 10"><span>VIEW GALLERY<i data-icon="1" class="icon"/></span><br />
        <span class="copyright" data-copy="© katyperry"/><br />
        <meta itemprop="width" content="auto"/><meta itemprop="height" content="auto"/>
</p>
<p>This is one of the couple&#8217;s first vacations after becoming parents.  The singer and the actor welcomed their first daughter together, Daisy, less than a year ago, on August 26, 2020. With her they have already organized a <strong>first getaway to Hawaii when little girl was seven months old</strong> And now that he has turned ten the next destination has been Italy.  In addition to the daughter of both, <strong>Little Flynn, 10, the son the actor had with Miranda Kerr, </strong>He has also traveled with them, as published in the magazine <em>People</em>, as well as other members of her family, including her pet Nugget with whom Katy poses in one of the snapshots. </p>
<p>The interpreter of songs like <em>Roar, Dark Horse y Harleys in Hawaii </em>has shared with his followers some images of his journey<strong> through the Venetian canals, enjoying a good seafood platter or the warm Mediterranean temperatures.</strong>  For his part, the interpreter of<em> The Lord of the Rings, Troy or The Hobbit</em> He also posted photos of him posing with Katy while enjoying a cocktail in a gondola.  During your visit through the canals <strong>the attractive couple did not miss the kiss under the bridge of sighs and immortalized the photo while Orlando wondered if it would bring them good luck</strong>, while she comments that &#8220;Cupid&#8217;s bow has once again done its thing with its arrow&#8221; along with another image in which they appear embraced.</p>
<p><strong>-The nice confession of Orlando Bloom about his daughter Daisy</strong></p>
<p>        <img loading="lazy" alt="Orlando Bloom y Katy Perry" itemprop="url" src="https://www.hola.com/imagenes/actualidad/20210617191604/orland-bloom-katy-perry-vacaciones-venecia/0-965-349/orlando-bloom1-z.jpg" width="auto" height="auto" title="The most romantic photos of Orlando Bloom and Katy Perry during their vacation in Venice 11"><span>VIEW GALLERY<i data-icon="1" class="icon"/></span><br />
        <span class="copyright" data-copy="© orlandobloom"/><br />
        <meta itemprop="width" content="auto"/><meta itemprop="height" content="auto"/>
</p>
<p>        <img loading="lazy" alt="Orlando Bloom y Katy Perry" itemprop="url" src="https://www.hola.com/imagenes/actualidad/20210617191604/orland-bloom-katy-perry-vacaciones-venecia/0-965-350/orlando-bloom2-z.jpg" width="auto" height="auto" title="The most romantic photos of Orlando Bloom and Katy Perry during their vacation in Venice 12"><span>VIEW GALLERY<i data-icon="1" class="icon"/></span><br />
        <span class="copyright" data-copy="© orlandobloom"/><br />
        <meta itemprop="width" content="auto"/><meta itemprop="height" content="auto"/>
</p>
<p>Katy, 36, and Orlando, 44, enjoy being parents.  Last summer, Daisy Dove Bloom, the first daughter of Katy and Orlando, came into the world a year and a half after the couple <strong>get engaged in a spectacular proposal for a hand</strong> over a helicopter on Valentine&#8217;s Day 2019. The artists began dating in 2016, following a first meeting at the Golden Globes, but they didn&#8217;t make it official and public until two years later, when they appeared together at <strong>a meeting with Pope Francis in the Vatican</strong>.  Previously, their relationship had experienced some ups and downs that Katy Perry has spoken of in recent interviews, a time when she did not feel herself and in which the pressure of her profession took its toll on her.  However, the love they felt for each other was stronger and today they form one of the strongest couples on the Hollywood scene.</p>
<p>Their wedding was postponed due to the pandemic and for now they are in no rush to say &#8216;yes, I do&#8217;.  For both of them it would be their second marriage. <strong>Orlando married Miranda Kerr in 2010</strong> and they divorced in 2013 after being the parents of little Flynn, although they continue to maintain a very good relationship for the sake of their son.  Coincidentally, the same year that the actor and the model said &#8216;yes, I want&#8217; they did the same <strong>Katy Perry and comedian Russel Brand</strong>, although their relationship lasted somewhat less.  In 2011 they broke up in the middle of the singer&#8217;s tour, after only 14 months of marriage.</p>
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<a href="https://www.hola.com/actualidad/20210617191604/orland-bloom-katy-perry-vacaciones-venecia/" target="_blank" rel="noopener">The most romantic photos of Orlando Bloom and Katy Perry during their vacation in Venice<br />
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";}s:7:"summary";s:666:"Orlando Bloom and Katy Perry enjoy some well deserved vacation with daughter Daisy Dove. The actor of Pirates of the Caribbean and the singer of Electric have traveled to Italy to spend a few days off in one of the most romantic cities in the world built on a lagoon in the north of the ... <a title="The most romantic photos of Orlando Bloom and Katy Perry during their vacation in Venice" class="read-more" href="https://celebritynews.fuzzyskunk.com/the-most-romantic-photos-of-orlando-bloom-and-katy-perry-during-their-vacation-in-venice/" aria-label="More on The most romantic photos of Orlando Bloom and Katy Perry during their vacation in Venice">Read more</a>";s:12:"atom_content";s:7150:"<div id="containerIntextAd">
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<p>Orlando Bloom and Katy Perry enjoy some<strong> well deserved vacation with daughter Daisy Dove</strong>.  The actor of <em>Pirates of the Caribbean</em> and the singer of<em> Electric</em> have traveled to Italy to spend a few days off in <strong>one of the most romantic cities in the world</strong> built on a lagoon in the north of the Adriatic Sea.  Gondola rides, photos under the Bridge of Sighs or most pleasant moments with your daughter in the vicinity of the well-known St. Mark&#8217;s Square have not been lacking in your visit through the incomparable and narrow alleys of the magical and monumental Venice.</p>
<p><strong>-The funny video of Katy Perry &#8216;sneaking&#8217; into Orlando Bloom&#8217;s pose</strong></p>
<p>        <img loading="lazy" alt="Katy Perry" itemprop="url" src="https://www.hola.com/imagenes/actualidad/20210617191604/orland-bloom-katy-perry-vacaciones-venecia/0-965-353/orlando-bloom5-a.jpg" width="auto" height="auto" title="The most romantic photos of Orlando Bloom and Katy Perry during their vacation in Venice 9"><span>VIEW GALLERY<i data-icon="1" class="icon"/></span><br />
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<p>        <img loading="lazy" alt="Katy Perry" itemprop="url" src="https://www.hola.com/imagenes/actualidad/20210617191604/orland-bloom-katy-perry-vacaciones-venecia/0-965-351/orlando-bloom4-a.jpg" width="auto" height="auto" title="The most romantic photos of Orlando Bloom and Katy Perry during their vacation in Venice 10"><span>VIEW GALLERY<i data-icon="1" class="icon"/></span><br />
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<p>This is one of the couple&#8217;s first vacations after becoming parents.  The singer and the actor welcomed their first daughter together, Daisy, less than a year ago, on August 26, 2020. With her they have already organized a <strong>first getaway to Hawaii when little girl was seven months old</strong> And now that he has turned ten the next destination has been Italy.  In addition to the daughter of both, <strong>Little Flynn, 10, the son the actor had with Miranda Kerr, </strong>He has also traveled with them, as published in the magazine <em>People</em>, as well as other members of her family, including her pet Nugget with whom Katy poses in one of the snapshots. </p>
<p>The interpreter of songs like <em>Roar, Dark Horse y Harleys in Hawaii </em>has shared with his followers some images of his journey<strong> through the Venetian canals, enjoying a good seafood platter or the warm Mediterranean temperatures.</strong>  For his part, the interpreter of<em> The Lord of the Rings, Troy or The Hobbit</em> He also posted photos of him posing with Katy while enjoying a cocktail in a gondola.  During your visit through the canals <strong>the attractive couple did not miss the kiss under the bridge of sighs and immortalized the photo while Orlando wondered if it would bring them good luck</strong>, while she comments that &#8220;Cupid&#8217;s bow has once again done its thing with its arrow&#8221; along with another image in which they appear embraced.</p>
<p><strong>-The nice confession of Orlando Bloom about his daughter Daisy</strong></p>
<p>        <img loading="lazy" alt="Orlando Bloom y Katy Perry" itemprop="url" src="https://www.hola.com/imagenes/actualidad/20210617191604/orland-bloom-katy-perry-vacaciones-venecia/0-965-349/orlando-bloom1-z.jpg" width="auto" height="auto" title="The most romantic photos of Orlando Bloom and Katy Perry during their vacation in Venice 11"><span>VIEW GALLERY<i data-icon="1" class="icon"/></span><br />
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<p>        <img loading="lazy" alt="Orlando Bloom y Katy Perry" itemprop="url" src="https://www.hola.com/imagenes/actualidad/20210617191604/orland-bloom-katy-perry-vacaciones-venecia/0-965-350/orlando-bloom2-z.jpg" width="auto" height="auto" title="The most romantic photos of Orlando Bloom and Katy Perry during their vacation in Venice 12"><span>VIEW GALLERY<i data-icon="1" class="icon"/></span><br />
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<p>Katy, 36, and Orlando, 44, enjoy being parents.  Last summer, Daisy Dove Bloom, the first daughter of Katy and Orlando, came into the world a year and a half after the couple <strong>get engaged in a spectacular proposal for a hand</strong> over a helicopter on Valentine&#8217;s Day 2019. The artists began dating in 2016, following a first meeting at the Golden Globes, but they didn&#8217;t make it official and public until two years later, when they appeared together at <strong>a meeting with Pope Francis in the Vatican</strong>.  Previously, their relationship had experienced some ups and downs that Katy Perry has spoken of in recent interviews, a time when she did not feel herself and in which the pressure of her profession took its toll on her.  However, the love they felt for each other was stronger and today they form one of the strongest couples on the Hollywood scene.</p>
<p>Their wedding was postponed due to the pandemic and for now they are in no rush to say &#8216;yes, I do&#8217;.  For both of them it would be their second marriage. <strong>Orlando married Miranda Kerr in 2010</strong> and they divorced in 2013 after being the parents of little Flynn, although they continue to maintain a very good relationship for the sake of their son.  Coincidentally, the same year that the actor and the model said &#8216;yes, I want&#8217; they did the same <strong>Katy Perry and comedian Russel Brand</strong>, although their relationship lasted somewhat less.  In 2011 they broke up in the middle of the singer&#8217;s tour, after only 14 months of marriage.</p>
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<br />
<a href="https://www.hola.com/actualidad/20210617191604/orland-bloom-katy-perry-vacaciones-venecia/" target="_blank" rel="noopener">The most romantic photos of Orlando Bloom and Katy Perry during their vacation in Venice<br />
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";s:14:"date_timestamp";i:1639791637;}i:7;a:11:{s:5:"title";s:69:"7 Julia Roberts Thrillers That Will Have You on the Edge of Your Seat";s:4:"link";s:107:"https://celebritynews.fuzzyskunk.com/7-julia-roberts-thrillers-that-will-have-you-on-the-edge-of-your-seat/";s:2:"dc";a:1:{s:7:"creator";s:15:"Pauline Moonlky";}s:7:"pubdate";s:31:"Sat, 18 Dec 2021 01:33:44 +0000";s:8:"category";s:44:"Trending PeopleEDGEJuliaRobertsSeatThrillers";s:4:"guid";s:45:"https://celebritynews.fuzzyskunk.com/?p=19414";s:11:"description";s:636:"No doubt about it, Julia Roberts is an icon in romantic-comedies, but she has quite the resume within the thriller genre as well. Alongside leading men such as George Clooney and Denzel Washington, Roberts is more than up to the task of taking on a government cover-up or two. Her characters don?t back down. They ... <a title="7 Julia Roberts Thrillers That Will Have You on the Edge of Your Seat" class="read-more" href="https://celebritynews.fuzzyskunk.com/7-julia-roberts-thrillers-that-will-have-you-on-the-edge-of-your-seat/" aria-label="More on 7 Julia Roberts Thrillers That Will Have You on the Edge of Your Seat">Read more</a>";s:7:"content";a:1:{s:7:"encoded";s:22013:"<div id="article-body">
<p>No doubt about it, <strong>Julia Roberts</strong> is an icon in romantic-comedies, but she has quite the resume within the thriller genre as well. Alongside leading men such as <strong>George Clooney</strong> and <strong>Denzel Washington</strong>, Roberts is more than up to the task of taking on a government cover-up or two. Her characters don?t back down. They have the tenacity to ensure the endgame works in their favor.</p>
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<p>The secret ingredient might just be her charisma. She&#8217;s known as America&#8217;s Sweetheart for a reason, going back to her star-making role in <strong><em>Pretty Woman</em></strong>. If she can find herself in one bad mess, maybe we all can. Nothing gets the adrenaline going than watching to see how she pulls herself out of a dire situation. Be it in sci-fi horror or a domestic thriller, you got to root for Julia.</p>
<p><span class="related-single">RELATED: Best Actress Winners of the 21st Century Ranked from Worst to Best</span></p>
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<h2 id="secret-in-their-eyes-2015">  Secret in Their Eyes (2015)</h2>
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<p>  This remake of an Argentine film, itself adapted from a novel by <strong>Eduardo Sacheri</strong>, puts Roberts in a very dark place. The story is shifted over to the United States, taking place in 2002, with the scars of 9/11 still fresh. Jess Cobb (Roberts) is an investigator for the LA attorney?s office, who learns her daughter has been murdered. When the suspect is brought in, justice isn?t so easy.</p>
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<p><strong>Nicole Kidman</strong> and <strong>Chiwetel Ejiofor</strong> are several of the other big names that get involved within the investigation. Grimmer than her other thrillers, happy endings aren?t to be found without a heavy bittersweetness. The themes of government corruption of the original film are changed to showcase the aftermath of 9/11 when the counterterrorism units made to protect citizens were possibly doing the complete opposite.</p>
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<h2 id="flatliners-1990">  Flatliners (1990)</h2>
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<img width="1920" height="1080" class="lazyload" alt="flatliners"/>
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<p>  What happens after death? Five medical students decide to find their own answer and the film?s title lets you in on how they&#8217;re going to do it. Each one takes a turn to flatline and essentially die, allowing their bodies to experience clinical death. Alongside Roberts in this one are some very well-known faces like Keifer Sutherland and <strong>Kevin Bacon, </strong>and for such an extreme premise, the remaining story needs an extra dose of something. So while it starts out in the science fiction genre, soon it leans more towards horror. Maye some questions should remain unanswered.</p>
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<p>With director <strong>Joel Schumacher</strong> at the helm, it&#8217;s a stylish ride through some spooky territory. More shocking than finding out the secrets to the afterlife could very well be the fact that this almost wasn&#8217;t a project Roberts signed on for. Schumacher very much wanted her onboard but someone else was close to <a target="_blank" href="https://ew.com/movies/2019/06/08/nicole-kidman-flatliners-julia-roberts-cinepocalypse/" rel="noopener noreferrer">taking over the role.</a> That would have been another young, up-and-coming actress at the time, none other than <strong>Nicole Kidman</strong>. Roberts ended up in the role but Kidman faired pretty well herself, creating her own acting legacy within Hollywood.</p>
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<h2 id="conspiracy-theory-1997">  Conspiracy Theory (1997)</h2>
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<p> <strong>Mel Gibson </strong>plays Jerry, a NYC cabbie on the verge of a mental breakdown. What?s keeping him going is the same thing making him fall apart. Conspiracy theories are part of his diet, the kind of &#8220;theories&#8221; that deal with global events being triggered by shady government involvements. But one just so happens to be true. He seeks out the help of Justice Department attorney Alice Sutton (Roberts) and the crazy ride keeps on getting crazier.</p>
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<p>This is a film that has a lot of ground to cover, very closely resembling Jerry&#8217;s state of mind. It includes MKUltra, the very true CIA human experimentation program often used by fiction writers to push the boundaries of what took place and what proved successful. It has <strong>Sir Patrick Stewart</strong> in a sinister role as a psychiatrist who sits on the complete opposite side of the moral compass compared to his famous role as Professor X. And through it all, Alice is there to believe in Jerry&#8217;s rants as best as she can but more importantly, try to stay alive herself.</p>
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<h2 id="money-monster-2016">  Money Monster (2016)</h2>
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<p>  Roberts teams up with her <em><strong>Ocean?s Eleven</strong></em>  costar <strong>George Clooney </strong>and the duo is directed by <strong>Jodie Foster</strong> in the actress&#8217; fourth feature-directing effort. Playing a Wall Street TV host, Clooney and his producer (Roberts), along with their crew, are taken hostage by an enraged young janitor (<strong>Jack O&#8217;Connell</strong>) who lost everything based on a tip from the show. Socioeconomic issues are brought to the screen and motives to the central crisis are made murky.</p>
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<p>While the two big stars spend more time off-screen from one another than onscreen, that distance benefits from the easy repertoire between them. The film plays on &#8220;real-time&#8221; suspense as the two try to figure out a way to diffuse the escalating crisis through an earpiece.</p>
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<h2 id="sleeping-with-the-enemy-1991">  Sleeping With the Enemy (1991)</h2>
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<p>  Laura Burney (Roberts) finally breaks free from her abusive husband, faking her death and leaving scenic Cape Cod behind. With her new identity as Sara Waters, she relocates to Iowa and slowly builds up a new life for herself. But this is a thriller, good things early on don?t last for long. This is the film that ended <em>Home Alone</em>?s 12-week long run at the top of the box office. It even broke records for the highest domestic opening of a film with a female lead.</p>
<p>Being only her second film in a leading role since <em>Pretty Woman</em>, this was a far different story compared to the rom-com classic. But a certain appeal was still there. You root for her characters and that&#8217;s more crucial than ever for Laura/Sara, who needs to escape from horrible domestic abuse.</p>
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<h2 id="the-pelican-brief-1993">  The Pelican Brief (1993)</h2>
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<p>  From director <strong>Alan J. Pakula</strong> (<em>All The President?s Men</em>), comes another political thriller. But if his past works in the genre proved too slow for you, maybe this might capture your attention. The main mystery reaches the highest level of the United States government and in doing so, goes for more dramatic flair than Pakula&#8217;s other more grounded thrillers. There?s a lot of known faces in the cast alongside Roberts, from Denzel Washington to <em>John Lithgow</em>. But bringing in Roberts is crucial for the character she plays.</p>
<p>As Darby Shaw, Roberts is a grad student that confidently goes deep into research for a paper and then just as quickly becomes insecure that it was all for nothing. Of course, that is anything but the truth. She gets caught up in a conspiracy with assassins and car bombs, forcing Darby to realize she can?t easily trust anyone.</p>
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<h2 id="homecoming-season-one-2018">  Homecoming: Season One (2018)</h2>
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<p>  Each of this show&#8217;s ten episodes had a runtime of a half-hour, if not less. This bite-sized love letter to the paranoid thrillers of the ?70s, directed by <strong>Sam Esmail</strong> (<em>Mr. Robot</em>), had something else special to it too. With Roberts in the main role of Heidi Bergman, it had fun at going against type for what fans have come to expect. Her charisma is drained of its energy during ?flash forward? segments of the story, remaining mostly to the &#8220;past&#8221;. It even brought in her onscreen sweetheart <strong>Dermot Mulroney</strong> from <em>My Best Friend?s Wedding</em> but stripped away the romance between them.</p>
<p>In playing two versions of Heidi, one where she is in control and one where she is not, <strong><em>Homecoming</em></strong>  might just be the best thriller she has done that shows off her range as an actress. Heidi can be warm and inviting and then distant and self-loathing. The cental mystery picks up speed with each episode, offering twists and turns all the way to the finale. But the best part is trying to figure out if Roberts may not be one of the good guys this time around.</p>
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            <strong><span class="next-btn-text-title">George Clooney, Julia Roberts, &#038; &#8216;Mamma Mia! 2&#8217; Director Are Making a Movie for All Moms</span></strong></p>
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<p>    <strong class="section-sub-title">About The Author</strong></p>
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<p>            <strong class="bio-title">Chris Sasaguay<br />
                                    <span class="amount">(21 Articles Published)</span><br />
                            </strong></p>
<div class="bio-desc">
<p>Chris Sasaguay is a Horror Features Writer for Collider. His passion in all the dark thrills of scary movies is thanks to a spooky childhood. Growing up, he visited family who lived in the Headless Horseman territory of Sleepy Hollow. Furthermore, if he should ever meet the iconic Jamie Lee Curtis, he?ll swiftly update his profile pic with the encounter. Stay tuned.</p>
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<p>                            More<br />
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<p>We  want to  give thanks to the  writer of this  post for this  incredible content<br />
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<a href="https://collider.com/best-julia-roberts-thriller-movies-tv-shows/" target="_blank" rel="noopener">7 Julia Roberts Thrillers That Will Have You on the Edge of Your Seat<br />
</a></p>
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";}s:7:"summary";s:636:"No doubt about it, Julia Roberts is an icon in romantic-comedies, but she has quite the resume within the thriller genre as well. Alongside leading men such as George Clooney and Denzel Washington, Roberts is more than up to the task of taking on a government cover-up or two. Her characters don?t back down. They ... <a title="7 Julia Roberts Thrillers That Will Have You on the Edge of Your Seat" class="read-more" href="https://celebritynews.fuzzyskunk.com/7-julia-roberts-thrillers-that-will-have-you-on-the-edge-of-your-seat/" aria-label="More on 7 Julia Roberts Thrillers That Will Have You on the Edge of Your Seat">Read more</a>";s:12:"atom_content";s:22013:"<div id="article-body">
<p>No doubt about it, <strong>Julia Roberts</strong> is an icon in romantic-comedies, but she has quite the resume within the thriller genre as well. Alongside leading men such as <strong>George Clooney</strong> and <strong>Denzel Washington</strong>, Roberts is more than up to the task of taking on a government cover-up or two. Her characters don?t back down. They have the tenacity to ensure the endgame works in their favor.</p>
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<p>The secret ingredient might just be her charisma. She&#8217;s known as America&#8217;s Sweetheart for a reason, going back to her star-making role in <strong><em>Pretty Woman</em></strong>. If she can find herself in one bad mess, maybe we all can. Nothing gets the adrenaline going than watching to see how she pulls herself out of a dire situation. Be it in sci-fi horror or a domestic thriller, you got to root for Julia.</p>
<p><span class="related-single">RELATED: Best Actress Winners of the 21st Century Ranked from Worst to Best</span></p>
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<h2 id="secret-in-their-eyes-2015">  Secret in Their Eyes (2015)</h2>
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<p>  This remake of an Argentine film, itself adapted from a novel by <strong>Eduardo Sacheri</strong>, puts Roberts in a very dark place. The story is shifted over to the United States, taking place in 2002, with the scars of 9/11 still fresh. Jess Cobb (Roberts) is an investigator for the LA attorney?s office, who learns her daughter has been murdered. When the suspect is brought in, justice isn?t so easy.</p>
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<p><strong>Nicole Kidman</strong> and <strong>Chiwetel Ejiofor</strong> are several of the other big names that get involved within the investigation. Grimmer than her other thrillers, happy endings aren?t to be found without a heavy bittersweetness. The themes of government corruption of the original film are changed to showcase the aftermath of 9/11 when the counterterrorism units made to protect citizens were possibly doing the complete opposite.</p>
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<h2 id="flatliners-1990">  Flatliners (1990)</h2>
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<p>  What happens after death? Five medical students decide to find their own answer and the film?s title lets you in on how they&#8217;re going to do it. Each one takes a turn to flatline and essentially die, allowing their bodies to experience clinical death. Alongside Roberts in this one are some very well-known faces like Keifer Sutherland and <strong>Kevin Bacon, </strong>and for such an extreme premise, the remaining story needs an extra dose of something. So while it starts out in the science fiction genre, soon it leans more towards horror. Maye some questions should remain unanswered.</p>
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<p>With director <strong>Joel Schumacher</strong> at the helm, it&#8217;s a stylish ride through some spooky territory. More shocking than finding out the secrets to the afterlife could very well be the fact that this almost wasn&#8217;t a project Roberts signed on for. Schumacher very much wanted her onboard but someone else was close to <a target="_blank" href="https://ew.com/movies/2019/06/08/nicole-kidman-flatliners-julia-roberts-cinepocalypse/" rel="noopener noreferrer">taking over the role.</a> That would have been another young, up-and-coming actress at the time, none other than <strong>Nicole Kidman</strong>. Roberts ended up in the role but Kidman faired pretty well herself, creating her own acting legacy within Hollywood.</p>
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<h2 id="conspiracy-theory-1997">  Conspiracy Theory (1997)</h2>
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<p> <strong>Mel Gibson </strong>plays Jerry, a NYC cabbie on the verge of a mental breakdown. What?s keeping him going is the same thing making him fall apart. Conspiracy theories are part of his diet, the kind of &#8220;theories&#8221; that deal with global events being triggered by shady government involvements. But one just so happens to be true. He seeks out the help of Justice Department attorney Alice Sutton (Roberts) and the crazy ride keeps on getting crazier.</p>
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<p>This is a film that has a lot of ground to cover, very closely resembling Jerry&#8217;s state of mind. It includes MKUltra, the very true CIA human experimentation program often used by fiction writers to push the boundaries of what took place and what proved successful. It has <strong>Sir Patrick Stewart</strong> in a sinister role as a psychiatrist who sits on the complete opposite side of the moral compass compared to his famous role as Professor X. And through it all, Alice is there to believe in Jerry&#8217;s rants as best as she can but more importantly, try to stay alive herself.</p>
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<h2 id="money-monster-2016">  Money Monster (2016)</h2>
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<p>  Roberts teams up with her <em><strong>Ocean?s Eleven</strong></em>  costar <strong>George Clooney </strong>and the duo is directed by <strong>Jodie Foster</strong> in the actress&#8217; fourth feature-directing effort. Playing a Wall Street TV host, Clooney and his producer (Roberts), along with their crew, are taken hostage by an enraged young janitor (<strong>Jack O&#8217;Connell</strong>) who lost everything based on a tip from the show. Socioeconomic issues are brought to the screen and motives to the central crisis are made murky.</p>
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<p>While the two big stars spend more time off-screen from one another than onscreen, that distance benefits from the easy repertoire between them. The film plays on &#8220;real-time&#8221; suspense as the two try to figure out a way to diffuse the escalating crisis through an earpiece.</p>
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<h2 id="sleeping-with-the-enemy-1991">  Sleeping With the Enemy (1991)</h2>
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<p>  Laura Burney (Roberts) finally breaks free from her abusive husband, faking her death and leaving scenic Cape Cod behind. With her new identity as Sara Waters, she relocates to Iowa and slowly builds up a new life for herself. But this is a thriller, good things early on don?t last for long. This is the film that ended <em>Home Alone</em>?s 12-week long run at the top of the box office. It even broke records for the highest domestic opening of a film with a female lead.</p>
<p>Being only her second film in a leading role since <em>Pretty Woman</em>, this was a far different story compared to the rom-com classic. But a certain appeal was still there. You root for her characters and that&#8217;s more crucial than ever for Laura/Sara, who needs to escape from horrible domestic abuse.</p>
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<h2 id="the-pelican-brief-1993">  The Pelican Brief (1993)</h2>
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<p>  From director <strong>Alan J. Pakula</strong> (<em>All The President?s Men</em>), comes another political thriller. But if his past works in the genre proved too slow for you, maybe this might capture your attention. The main mystery reaches the highest level of the United States government and in doing so, goes for more dramatic flair than Pakula&#8217;s other more grounded thrillers. There?s a lot of known faces in the cast alongside Roberts, from Denzel Washington to <em>John Lithgow</em>. But bringing in Roberts is crucial for the character she plays.</p>
<p>As Darby Shaw, Roberts is a grad student that confidently goes deep into research for a paper and then just as quickly becomes insecure that it was all for nothing. Of course, that is anything but the truth. She gets caught up in a conspiracy with assassins and car bombs, forcing Darby to realize she can?t easily trust anyone.</p>
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<h2 id="homecoming-season-one-2018">  Homecoming: Season One (2018)</h2>
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<p>  Each of this show&#8217;s ten episodes had a runtime of a half-hour, if not less. This bite-sized love letter to the paranoid thrillers of the ?70s, directed by <strong>Sam Esmail</strong> (<em>Mr. Robot</em>), had something else special to it too. With Roberts in the main role of Heidi Bergman, it had fun at going against type for what fans have come to expect. Her charisma is drained of its energy during ?flash forward? segments of the story, remaining mostly to the &#8220;past&#8221;. It even brought in her onscreen sweetheart <strong>Dermot Mulroney</strong> from <em>My Best Friend?s Wedding</em> but stripped away the romance between them.</p>
<p>In playing two versions of Heidi, one where she is in control and one where she is not, <strong><em>Homecoming</em></strong>  might just be the best thriller she has done that shows off her range as an actress. Heidi can be warm and inviting and then distant and self-loathing. The cental mystery picks up speed with each episode, offering twists and turns all the way to the finale. But the best part is trying to figure out if Roberts may not be one of the good guys this time around.</p>
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                            <img width="3504" height="1752" class="lazyload" alt="Julia Roberts and George Clooney in Ocean's Twelve"/>
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<div class="next-btn-text lines-trim">
            <strong><span class="next-btn-text-title">George Clooney, Julia Roberts, &#038; &#8216;Mamma Mia! 2&#8217; Director Are Making a Movie for All Moms</span></strong></p>
<p class="next-btn-text-p">&#8216;Ticket to Paradise&#8217; just sounds nice!</p>
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<p>Read Next</p>
<p>                                                <!-- No winning ad found for zone: below next button! --><br />
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<p>    <strong class="section-sub-title">About The Author</strong></p>
<div class="w-article-author-bio">
<div class="author-bio-img"></div>
<div class="author-bio-text">
<p>            <strong class="bio-title">Chris Sasaguay<br />
                                    <span class="amount">(21 Articles Published)</span><br />
                            </strong></p>
<div class="bio-desc">
<p>Chris Sasaguay is a Horror Features Writer for Collider. His passion in all the dark thrills of scary movies is thanks to a spooky childhood. Growing up, he visited family who lived in the Headless Horseman territory of Sleepy Hollow. Furthermore, if he should ever meet the iconic Jamie Lee Curtis, he?ll swiftly update his profile pic with the encounter. Stay tuned.</p>
</p></div>
<p>                            More<br />
                    From Chris Sasaguay
                    </p></div>
</p></div>
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                                </div>
<p>We  want to  give thanks to the  writer of this  post for this  incredible content<br />
<br />
<a href="https://collider.com/best-julia-roberts-thriller-movies-tv-shows/" target="_blank" rel="noopener">7 Julia Roberts Thrillers That Will Have You on the Edge of Your Seat<br />
</a></p>
<p><center><iframe loading="lazy" src="http://wiki.gentilsvirus.org/extensions/magpierss-0.72/scripts/magpie_slashbox.php?rss_url=http://feeds.feedburner.com/Bbc-edition" height="25" width="250" title=""></iframe></center></p>
";s:14:"date_timestamp";i:1639791224;}i:8;a:11:{s:5:"title";s:82:"Soft semiconductors that stretch like human skin can detect ultra-low light levels";s:4:"link";s:120:"https://celebritynews.fuzzyskunk.com/soft-semiconductors-that-stretch-like-human-skin-can-detect-ultra-low-light-levels/";s:2:"dc";a:1:{s:7:"creator";s:12:"Tony Grantly";}s:7:"pubdate";s:31:"Sat, 18 Dec 2021 01:27:31 +0000";s:8:"category";s:77:"Health And Sciencedetecthumanlevelslightsemiconductorsskinsoftstretchultralow";s:4:"guid";s:45:"https://celebritynews.fuzzyskunk.com/?p=19409";s:11:"description";s:761:"Journal Reference: Youngrak Park, Canek Fuentes-Hernandez, Kyungjin Kim, Wen-Fang Chou, Felipe A. Larrain, Samuel Graham, Olivier N. Pierron, Bernard Kippelen. Skin-like low-noise elastomeric organic photodiodes. Science Advances, 2021; 7 (51) DOI: 10.1126/sciadv.abj6565 Georgia Tech researchers have created a material that acts like a second skin layer and is up to 200% more stretchable than its ... <a title="Soft semiconductors that stretch like human skin can detect ultra-low light levels" class="read-more" href="https://celebritynews.fuzzyskunk.com/soft-semiconductors-that-stretch-like-human-skin-can-detect-ultra-low-light-levels/" aria-label="More on Soft semiconductors that stretch like human skin can detect ultra-low light levels">Read more</a>";s:7:"content";a:1:{s:7:"encoded";s:8268:"<div>
<p><strong>Journal Reference</strong>:</p>
<ol class="journal">
<li>Youngrak Park, Canek Fuentes-Hernandez, Kyungjin Kim, Wen-Fang Chou, Felipe A. Larrain, Samuel Graham, Olivier N. Pierron, Bernard Kippelen. <strong>Skin-like low-noise elastomeric organic photodiodes</strong>. Science Advances, 2021; 7 (51) DOI: <a rel="nofollow noopener" href="https://dx.doi.org/10.1126/sciadv.abj6565" target="_blank">10.1126/sciadv.abj6565</a>
</li>
</ol>
<p>Georgia Tech researchers have created a material that acts like a second skin layer and is up to 200% more stretchable than its original dimension without significantly losing its electric current. The researchers say the soft flexible photodetectors could enhance the utility of medical wearable sensors and implantable devices, among other applications. The research will be published on Dec. 15 in the journal Science Advances.</p>
<p>Georgia Tech researchers from both mechanical and computing engineering labs collaborated over three years to demonstrate a new level of stretchability for a photodetector, a device made from a synthetic polymer and an elastomer that absorbs light to produce an electrical current.</p>
<p>Photodetectors today are used as wearables for health monitoring, such as rigid fingertip pulse oximeter reading devices. They convert light signals into electrical ones and are commonly used on wearable electronics.</p>
<p><strong>Stretchable like a Rubber Band</strong></p>
<p>Given that conventional flexible semiconductors break under a few percentages of strain, the Georgia Tech findings are ?an order-of-magnitude improvement,? said Olivier Pierron, professor in the George W. Woodruff School of Mechanical Engineering, whose lab measures the mechanical properties and reliability of flexible electronics under extreme conditions.</p>
<p>?Think of a rubber band or something that?s soft and stretchable like human skin yet has similar electrical semiconducting properties of solid or rigid semiconductors,? said Canek Fuentes-Hernandez, a co-PI formerly in the School of Electrical and Computer Engineering (ECE) and now an associate professor in Electrical and Computer Engineering at Northeastern University in Boston. ?We?ve shown that you can build stretchability into semiconductors that retains the electrical performance needed to detect light levels that are around hundred million times fainter than produced by a light bulb used for indoor illumination,? he said.</p>
<p><strong>Extraordinary Tenacity and Teamwork </strong></p>
<p>Bernard Kippelen, vice provost for International Initiatives and an ECE professor, oversaw the work of Youngrak Park, the study?s first author and a Ph.D. candidate in ECE. Following two-and-a-half years of research, Park uncovered the right combination of chemical compounds that produced a super-soft material with the ability to generate and conduct electricity when exposed to light.</p>
<p>Park found the perfect ratio for all parts of the semiconductor layer to maintain high performance in the photodetector. But it was painstaking work to prove the materials? stretchability, especially given that a single layer was 1,000 times thinner than a human hair.</p>
<p>Park relied on Kyungjin Kim, then a Georgia Tech Ph.D. mechanical engineering student, to test the material?s reliability. He continued to provide Kim with larger, thicker samples until one with a thickness of 500 nanometers worked.</p>
<p>?It was still super thin. Under dry conditions, it would just crumble. We had to use a water reservoir to keep its shape,? recalled Kim, now an assistant professor in the University of Connecticut?s Department of Mechanical Engineering.</p>
<p>Elaborating on how difficult it was to measure pure mechanical properties of a photoactive layer, Pierron noted, ?Electronic devices are very brittle typically, which is okay with conventional devices fabricated on rigid substrates. But as soon as you use soft substrates that becomes an issue.?</p>
<p>The water acted like plastic wrap keeping the thin films in place without crumbling or losing shape, enabling the researchers to stretch the material and measure its mechanical properties.</p>
<p>To test for electrical signals coming out of the device under illumination, electronic terminals had to be embedded on it. Yet, those terminals had to be deformable, too, or the entire device would become rigid.</p>
<p>?Fabricating stretchable electronic terminals was a major challenge in and of itself,? said ECE PhD graduate Felipe Andres Larrain, who worked closely with Park and focused on the embedded components. He is now an assistant professor at Adolfo Ibáñez University in Chile.</p>
<p>While this breakthrough material has been initially integrated into a photodetector and tested for electrical functionality, more testing and optimization is needed to show the materials? stretchability under multimodal loads and its shelf stability.</p>
<p>?What?s exciting is what these materials and the devices will enable us to develop?namely, the concept of intelligence systems. You have functional surfaces that combine sensors that monitor all kinds of physical properties,? said Graham, former chair of the Woodruff School of Mechanical Engineering and now Dean of Engineering at the University of Maryland.</p>
<p>?This is a very good example of interdisciplinary research ? none of this work would have been possible without the collaboration between electrical and mechanical engineers,? Kippelen said. ?In the lab we didn?t have any prior experience with stretchable materials. Figuring out how to measure this took a lot of perseverance, creativity and hard work.?</p>
<p><strong>New Smart Applications Possible</strong></p>
<p>The researchers are most excited about the potential of the material to enhance medical wearables. Typically, wristwatches that use rigid biosensors have limitations since flexing the wrist can completely change the sensor?s measurements. They are subject to ?motion artifact,? or degraded image quality, caused when a person moves.</p>
<p>?Moving around can drastically affect the usability of collected data but being able to reposition devices on the body to minimize or eliminate motion artifact is a big deal,? noted Gabriel Cahn, a project manager for Huxley Medical, a biosensor startup in Atlanta, who recently graduated from Georgia Tech with a doctorate in flexible electronics. ?Having electronics that can flex, twist, bend and conform to non-flat surfaces and move with your body will allow you to place these sensors in more advantageous places to collect biometric data. It will be infinitely more useful in helping diagnose or monitor existing medical illnesses.?</p>
<p>The research team foresees rich applications for the soft and stretchable polymer blend beyond wearables for health monitoring. ?The soft device also could be attractive for implantable electronics for bio-electronic applications since the interfaces comply with the dynamic motion of the soft biological tissues, reducing the foreign body reaction,? said Kim.</p>
<p>?The potential is fantastic,? added Larrain. ?In the long-term, you could develop sensors that could enhance or even replace the human eye or be applied to robotic eyes.?</p>
<p>Fuentes sees the material working in smart agriculture applications, where farmers could attach light sensors into fruits or other produce to monitor growth, disease and to better time harvesting.</p>
<p>Kippelen believes the rubber-like photodiodes that detect ultralow light levels could find applications in detecting, identifying, and characterizing ionizing radiation for nuclear fuel cycle monitoring.</p>
</div>
<p>We  want to  give thanks to the author of this article for this  incredible  material<br />
<br />
<a href="https://novlink.co/soft-semiconductors-that-stretch-like-human-skin-can-detect-ultra-low-light-levels/" target="_blank" rel="noopener">Soft semiconductors that stretch like human skin can detect ultra-low light levels</a></p>
<p><center><iframe loading="lazy" src="http://tuvalu.santafe.edu/rss/magpierss-0.72/scripts/magpie_debug.php?url=http://feeds.feedburner.com/DentistNewsNetwork" height="25" width="250" title=""></iframe></center></p>
";}s:7:"summary";s:761:"Journal Reference: Youngrak Park, Canek Fuentes-Hernandez, Kyungjin Kim, Wen-Fang Chou, Felipe A. Larrain, Samuel Graham, Olivier N. Pierron, Bernard Kippelen. Skin-like low-noise elastomeric organic photodiodes. Science Advances, 2021; 7 (51) DOI: 10.1126/sciadv.abj6565 Georgia Tech researchers have created a material that acts like a second skin layer and is up to 200% more stretchable than its ... <a title="Soft semiconductors that stretch like human skin can detect ultra-low light levels" class="read-more" href="https://celebritynews.fuzzyskunk.com/soft-semiconductors-that-stretch-like-human-skin-can-detect-ultra-low-light-levels/" aria-label="More on Soft semiconductors that stretch like human skin can detect ultra-low light levels">Read more</a>";s:12:"atom_content";s:8268:"<div>
<p><strong>Journal Reference</strong>:</p>
<ol class="journal">
<li>Youngrak Park, Canek Fuentes-Hernandez, Kyungjin Kim, Wen-Fang Chou, Felipe A. Larrain, Samuel Graham, Olivier N. Pierron, Bernard Kippelen. <strong>Skin-like low-noise elastomeric organic photodiodes</strong>. Science Advances, 2021; 7 (51) DOI: <a rel="nofollow noopener" href="https://dx.doi.org/10.1126/sciadv.abj6565" target="_blank">10.1126/sciadv.abj6565</a>
</li>
</ol>
<p>Georgia Tech researchers have created a material that acts like a second skin layer and is up to 200% more stretchable than its original dimension without significantly losing its electric current. The researchers say the soft flexible photodetectors could enhance the utility of medical wearable sensors and implantable devices, among other applications. The research will be published on Dec. 15 in the journal Science Advances.</p>
<p>Georgia Tech researchers from both mechanical and computing engineering labs collaborated over three years to demonstrate a new level of stretchability for a photodetector, a device made from a synthetic polymer and an elastomer that absorbs light to produce an electrical current.</p>
<p>Photodetectors today are used as wearables for health monitoring, such as rigid fingertip pulse oximeter reading devices. They convert light signals into electrical ones and are commonly used on wearable electronics.</p>
<p><strong>Stretchable like a Rubber Band</strong></p>
<p>Given that conventional flexible semiconductors break under a few percentages of strain, the Georgia Tech findings are ?an order-of-magnitude improvement,? said Olivier Pierron, professor in the George W. Woodruff School of Mechanical Engineering, whose lab measures the mechanical properties and reliability of flexible electronics under extreme conditions.</p>
<p>?Think of a rubber band or something that?s soft and stretchable like human skin yet has similar electrical semiconducting properties of solid or rigid semiconductors,? said Canek Fuentes-Hernandez, a co-PI formerly in the School of Electrical and Computer Engineering (ECE) and now an associate professor in Electrical and Computer Engineering at Northeastern University in Boston. ?We?ve shown that you can build stretchability into semiconductors that retains the electrical performance needed to detect light levels that are around hundred million times fainter than produced by a light bulb used for indoor illumination,? he said.</p>
<p><strong>Extraordinary Tenacity and Teamwork </strong></p>
<p>Bernard Kippelen, vice provost for International Initiatives and an ECE professor, oversaw the work of Youngrak Park, the study?s first author and a Ph.D. candidate in ECE. Following two-and-a-half years of research, Park uncovered the right combination of chemical compounds that produced a super-soft material with the ability to generate and conduct electricity when exposed to light.</p>
<p>Park found the perfect ratio for all parts of the semiconductor layer to maintain high performance in the photodetector. But it was painstaking work to prove the materials? stretchability, especially given that a single layer was 1,000 times thinner than a human hair.</p>
<p>Park relied on Kyungjin Kim, then a Georgia Tech Ph.D. mechanical engineering student, to test the material?s reliability. He continued to provide Kim with larger, thicker samples until one with a thickness of 500 nanometers worked.</p>
<p>?It was still super thin. Under dry conditions, it would just crumble. We had to use a water reservoir to keep its shape,? recalled Kim, now an assistant professor in the University of Connecticut?s Department of Mechanical Engineering.</p>
<p>Elaborating on how difficult it was to measure pure mechanical properties of a photoactive layer, Pierron noted, ?Electronic devices are very brittle typically, which is okay with conventional devices fabricated on rigid substrates. But as soon as you use soft substrates that becomes an issue.?</p>
<p>The water acted like plastic wrap keeping the thin films in place without crumbling or losing shape, enabling the researchers to stretch the material and measure its mechanical properties.</p>
<p>To test for electrical signals coming out of the device under illumination, electronic terminals had to be embedded on it. Yet, those terminals had to be deformable, too, or the entire device would become rigid.</p>
<p>?Fabricating stretchable electronic terminals was a major challenge in and of itself,? said ECE PhD graduate Felipe Andres Larrain, who worked closely with Park and focused on the embedded components. He is now an assistant professor at Adolfo Ibáñez University in Chile.</p>
<p>While this breakthrough material has been initially integrated into a photodetector and tested for electrical functionality, more testing and optimization is needed to show the materials? stretchability under multimodal loads and its shelf stability.</p>
<p>?What?s exciting is what these materials and the devices will enable us to develop?namely, the concept of intelligence systems. You have functional surfaces that combine sensors that monitor all kinds of physical properties,? said Graham, former chair of the Woodruff School of Mechanical Engineering and now Dean of Engineering at the University of Maryland.</p>
<p>?This is a very good example of interdisciplinary research ? none of this work would have been possible without the collaboration between electrical and mechanical engineers,? Kippelen said. ?In the lab we didn?t have any prior experience with stretchable materials. Figuring out how to measure this took a lot of perseverance, creativity and hard work.?</p>
<p><strong>New Smart Applications Possible</strong></p>
<p>The researchers are most excited about the potential of the material to enhance medical wearables. Typically, wristwatches that use rigid biosensors have limitations since flexing the wrist can completely change the sensor?s measurements. They are subject to ?motion artifact,? or degraded image quality, caused when a person moves.</p>
<p>?Moving around can drastically affect the usability of collected data but being able to reposition devices on the body to minimize or eliminate motion artifact is a big deal,? noted Gabriel Cahn, a project manager for Huxley Medical, a biosensor startup in Atlanta, who recently graduated from Georgia Tech with a doctorate in flexible electronics. ?Having electronics that can flex, twist, bend and conform to non-flat surfaces and move with your body will allow you to place these sensors in more advantageous places to collect biometric data. It will be infinitely more useful in helping diagnose or monitor existing medical illnesses.?</p>
<p>The research team foresees rich applications for the soft and stretchable polymer blend beyond wearables for health monitoring. ?The soft device also could be attractive for implantable electronics for bio-electronic applications since the interfaces comply with the dynamic motion of the soft biological tissues, reducing the foreign body reaction,? said Kim.</p>
<p>?The potential is fantastic,? added Larrain. ?In the long-term, you could develop sensors that could enhance or even replace the human eye or be applied to robotic eyes.?</p>
<p>Fuentes sees the material working in smart agriculture applications, where farmers could attach light sensors into fruits or other produce to monitor growth, disease and to better time harvesting.</p>
<p>Kippelen believes the rubber-like photodiodes that detect ultralow light levels could find applications in detecting, identifying, and characterizing ionizing radiation for nuclear fuel cycle monitoring.</p>
</div>
<p>We  want to  give thanks to the author of this article for this  incredible  material<br />
<br />
<a href="https://novlink.co/soft-semiconductors-that-stretch-like-human-skin-can-detect-ultra-low-light-levels/" target="_blank" rel="noopener">Soft semiconductors that stretch like human skin can detect ultra-low light levels</a></p>
<p><center><iframe loading="lazy" src="http://tuvalu.santafe.edu/rss/magpierss-0.72/scripts/magpie_debug.php?url=http://feeds.feedburner.com/DentistNewsNetwork" height="25" width="250" title=""></iframe></center></p>
";s:14:"date_timestamp";i:1639790851;}i:9;a:11:{s:5:"title";s:78:"Researchers first to predict when bacteria may become resistant to antibiotics";s:4:"link";s:116:"https://celebritynews.fuzzyskunk.com/researchers-first-to-predict-when-bacteria-may-become-resistant-to-antibiotics/";s:2:"dc";a:1:{s:7:"creator";s:12:"Tony Grantly";}s:7:"pubdate";s:31:"Sat, 18 Dec 2021 00:10:29 +0000";s:8:"category";s:64:"Health And ScienceantibioticsbacteriapredictResearchersresistant";s:4:"guid";s:45:"https://celebritynews.fuzzyskunk.com/?p=19404";s:11:"description";s:760:"Journal Reference: Arturo Torres Ortiz, Jorge Coronel, Julia Rios Vidal, Cesar Bonilla, David A. J. Moore, Robert H. Gilman, Francois Balloux, Onn Min Kon, Xavier Didelot, Louis Grandjean. Genomic signatures of pre-resistance in Mycobacterium tuberculosis. Nature Communications, 2021; 12 (1) DOI: 10.1038/s41467-021-27616-7 The findings, published in Nature Communications, will allow doctors in the future to ... <a title="Researchers first to predict when bacteria may become resistant to antibiotics" class="read-more" href="https://celebritynews.fuzzyskunk.com/researchers-first-to-predict-when-bacteria-may-become-resistant-to-antibiotics/" aria-label="More on Researchers first to predict when bacteria may become resistant to antibiotics">Read more</a>";s:7:"content";a:1:{s:7:"encoded";s:4785:"<div>
<p><strong>Journal Reference</strong>:</p>
<ol class="journal">
<li>Arturo Torres Ortiz, Jorge Coronel, Julia Rios Vidal, Cesar Bonilla, David A. J. Moore, Robert H. Gilman, Francois Balloux, Onn Min Kon, Xavier Didelot, Louis Grandjean. <strong>Genomic signatures of pre-resistance in Mycobacterium tuberculosis</strong>. Nature Communications, 2021; 12 (1) DOI: <a rel="nofollow noopener" href="https://dx.doi.org/10.1038/s41467-021-27616-7" target="_blank">10.1038/s41467-021-27616-7</a>
</li>
</ol>
<p>The findings, published in Nature Communications, will allow doctors in the future to select the best treatments for bacterial infections.</p>
<p>The team led by Great Ormond Street Hospital (GOSH) and the UCL Great Ormond Street Institute of Child Health, in collaboration with the Peruvian Tuberculosis programme and funded by Wellcome and the National Institutes of Health (USA), sequenced the full genomes of over 3,000 tuberculosis (TB) samples, tracing TB infections back through patients over nearly two decades.</p>
<p>Mycobacterium tuberculosis (TB) is a bacterial infection that largely affects the lungs. It was the second leading infectious cause of death after COVID-19 in 2020, killing 1.5m people. It can be cured if treated with the right antibiotics, but treatment is lengthy and many people most at risk lack access to adequate healthcare. Drug-resistant TB can develop when people do not finish their full course of treatment, or when drugs are not available or are of poor quality.</p>
<p>Multi-drug resistant TB represents a huge, unsustainable burden and totally drug resistant strains have been detected in a handful of countries. As health systems struggle to cope with the pandemic, progress on TB treatment globally has slowed.</p>
<p>In order to develop a better understanding of, and ultimately better treatments for, TB, this new research has identified for the first time how to pre-empt drug resistance mutations before they have occurred. The researchers have termed this concept ?pre-resistance?: when a disease-causing organism ? such as a virus or bacteria ? has a greater inherent risk of developing resistance to drugs in the future.</p>
<p>By analysing thousands of bacterial genomes, the study has the potential to be applied to other infectious diseases and paves the way towards personalised pathogen ?genomic therapy? ? where drugs are selected based on the DNA of the specific pathogen causing the illness, preventing drug resistance from developing.</p>
<p>The work is the culmination of 17 years? research in the suburbs of Lima, Peru, where Dr Louis Grandjean, Consultant in Infectious Diseases at GOSH and Associate Professor at UCL Great Ormond Street Institute of Child Health, leads a research group.</p>
<p>The international team compared tuberculosis samples from 3,135 different samples to reconstruct a TB bacterial ?family tree? ? known as phylogeny. The team then used computational analysis to identify the ancestral genetic code of bacteria that then went on to develop drug resistance. The team identified the key changes associated with the development of resistance by looking through the ?branches? of the family tree to see which were the most likely to go on to develop drug resistance.</p>
<p>The authors described how variations in the TB genome predicted that a particular branch would likely become drug resistant, and then validated their findings in an independent global TB data set.</p>
<p>Dr Grandjean, senior author of the international study, said: ?We?re running out of options in antibiotics and the options we have are often toxic ? we have to get smarter at using what we have to prevent drug resistance.</p>
<p>?This is the first example of showing that we can get ahead of drug resistance. That will allow us in the future to use the pathogen genome to select the best treatments.?</p>
<p>PhD student Arturo Torres Ortiz (UCL Great Ormond Street Institute of Child Health), first author of the paper, said: ?We hope this discovery could provide a way of treating difficult conditions in the future by targeting specific pathogen genomes that are most likely to become drug resistant in the future.?</p>
</div>
<p>We would like to thank the author of this  short article for this awesome content<br />
<br />
<a href="https://novlink.co/researchers-first-to-predict-when-bacteria-may-become-resistant-to-antibiotics/" target="_blank" rel="noopener">Researchers first to predict when bacteria may become resistant to antibiotics</a></p>
<p><center><iframe loading="lazy" src="http://unistudyguides.com/bluespice-mw/ext-dist/RSS-Topdate/scripts/magpie_slashbox.php?rss_url=https://celebritynews.fuzzyskunk.com/feed" height="25" width="250" title=""></iframe></center></p>
";}s:7:"summary";s:760:"Journal Reference: Arturo Torres Ortiz, Jorge Coronel, Julia Rios Vidal, Cesar Bonilla, David A. J. Moore, Robert H. Gilman, Francois Balloux, Onn Min Kon, Xavier Didelot, Louis Grandjean. Genomic signatures of pre-resistance in Mycobacterium tuberculosis. Nature Communications, 2021; 12 (1) DOI: 10.1038/s41467-021-27616-7 The findings, published in Nature Communications, will allow doctors in the future to ... <a title="Researchers first to predict when bacteria may become resistant to antibiotics" class="read-more" href="https://celebritynews.fuzzyskunk.com/researchers-first-to-predict-when-bacteria-may-become-resistant-to-antibiotics/" aria-label="More on Researchers first to predict when bacteria may become resistant to antibiotics">Read more</a>";s:12:"atom_content";s:4785:"<div>
<p><strong>Journal Reference</strong>:</p>
<ol class="journal">
<li>Arturo Torres Ortiz, Jorge Coronel, Julia Rios Vidal, Cesar Bonilla, David A. J. Moore, Robert H. Gilman, Francois Balloux, Onn Min Kon, Xavier Didelot, Louis Grandjean. <strong>Genomic signatures of pre-resistance in Mycobacterium tuberculosis</strong>. Nature Communications, 2021; 12 (1) DOI: <a rel="nofollow noopener" href="https://dx.doi.org/10.1038/s41467-021-27616-7" target="_blank">10.1038/s41467-021-27616-7</a>
</li>
</ol>
<p>The findings, published in Nature Communications, will allow doctors in the future to select the best treatments for bacterial infections.</p>
<p>The team led by Great Ormond Street Hospital (GOSH) and the UCL Great Ormond Street Institute of Child Health, in collaboration with the Peruvian Tuberculosis programme and funded by Wellcome and the National Institutes of Health (USA), sequenced the full genomes of over 3,000 tuberculosis (TB) samples, tracing TB infections back through patients over nearly two decades.</p>
<p>Mycobacterium tuberculosis (TB) is a bacterial infection that largely affects the lungs. It was the second leading infectious cause of death after COVID-19 in 2020, killing 1.5m people. It can be cured if treated with the right antibiotics, but treatment is lengthy and many people most at risk lack access to adequate healthcare. Drug-resistant TB can develop when people do not finish their full course of treatment, or when drugs are not available or are of poor quality.</p>
<p>Multi-drug resistant TB represents a huge, unsustainable burden and totally drug resistant strains have been detected in a handful of countries. As health systems struggle to cope with the pandemic, progress on TB treatment globally has slowed.</p>
<p>In order to develop a better understanding of, and ultimately better treatments for, TB, this new research has identified for the first time how to pre-empt drug resistance mutations before they have occurred. The researchers have termed this concept ?pre-resistance?: when a disease-causing organism ? such as a virus or bacteria ? has a greater inherent risk of developing resistance to drugs in the future.</p>
<p>By analysing thousands of bacterial genomes, the study has the potential to be applied to other infectious diseases and paves the way towards personalised pathogen ?genomic therapy? ? where drugs are selected based on the DNA of the specific pathogen causing the illness, preventing drug resistance from developing.</p>
<p>The work is the culmination of 17 years? research in the suburbs of Lima, Peru, where Dr Louis Grandjean, Consultant in Infectious Diseases at GOSH and Associate Professor at UCL Great Ormond Street Institute of Child Health, leads a research group.</p>
<p>The international team compared tuberculosis samples from 3,135 different samples to reconstruct a TB bacterial ?family tree? ? known as phylogeny. The team then used computational analysis to identify the ancestral genetic code of bacteria that then went on to develop drug resistance. The team identified the key changes associated with the development of resistance by looking through the ?branches? of the family tree to see which were the most likely to go on to develop drug resistance.</p>
<p>The authors described how variations in the TB genome predicted that a particular branch would likely become drug resistant, and then validated their findings in an independent global TB data set.</p>
<p>Dr Grandjean, senior author of the international study, said: ?We?re running out of options in antibiotics and the options we have are often toxic ? we have to get smarter at using what we have to prevent drug resistance.</p>
<p>?This is the first example of showing that we can get ahead of drug resistance. That will allow us in the future to use the pathogen genome to select the best treatments.?</p>
<p>PhD student Arturo Torres Ortiz (UCL Great Ormond Street Institute of Child Health), first author of the paper, said: ?We hope this discovery could provide a way of treating difficult conditions in the future by targeting specific pathogen genomes that are most likely to become drug resistant in the future.?</p>
</div>
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<a href="https://novlink.co/researchers-first-to-predict-when-bacteria-may-become-resistant-to-antibiotics/" target="_blank" rel="noopener">Researchers first to predict when bacteria may become resistant to antibiotics</a></p>
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